Control of neglected tropical diseases

PJ Hotez, DH Molyneux, A Fenwick… - New England journal …, 2007 - Mass Medical Soc
In addition to malaria, tuberculosis, and human immunodeficiency virus infection, several
other infectious diseases are associated with substantial morbidity and mortality. In …

Current drug therapy and pharmaceutical challenges for Chagas disease

J Bermudez, C Davies, A Simonazzi, JP Real, S Palma - Acta tropica, 2016 - Elsevier
One of the most significant health problems in the American continent in terms of human
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …

[HTML][HTML] Recent advances in leishmaniasis treatment

TS Tiuman, AO Santos, T Ueda-Nakamura… - International Journal of …, 2011 - Elsevier
About 1.5 million new cases of cutaneous leishmaniasis and 500 000 new cases of visceral
leishmaniasis occur each year around the world. For over half a century, the clinical forms of …

Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches

JA Urbina - Acta tropica, 2010 - Elsevier
A critical review of the development of specific chemotherapeutic approaches for the
management of American Trypanosomiasis or Chagas disease is presented, including …

Cameroonian medicinal plants: pharmacology and derived natural products

V Kuete, T Efferth - Frontiers in pharmacology, 2010 - frontiersin.org
Many develo** countries including Cameroon have mortality patterns that reflect high
levels of infectious diseases and the risk of death during pregnancy and childbirth, in …

SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis

RT Jacobs, B Nare, SA Wring, MD Orr… - PLoS neglected …, 2011 - journals.plos.org
Background Human African trypanosomiasis (HAT) is an important public health problem in
sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need exists …

Parasitic diseases: liposomes and polymeric nanoparticles versus lipid nanoparticles

AA Date, MD Joshi, VB Patravale - Advanced drug delivery reviews, 2007 - Elsevier
Parasitic diseases such as malaria, leishmaniasis, and trypanosomiasis represent a
significant global burden and pose a great challenge to drug discovery and delivery …

A review on the occurrence of companion vector-borne diseases in pet animals in Latin America

RG Maggi, F Krämer - Parasites & vectors, 2019 - Springer
Companion vector-borne diseases (CVBDs) are an important threat for pet life, but may also
have an impact on human health, due to their often zoonotic character. The importance and …

Amphotericin B formulations and drug targeting

JJ Torrado, R Espada, MP Ballesteros… - Journal of …, 2008 - Elsevier
Amphotericin B is a low-soluble polyene antibiotic which is able to self-aggregate. The
aggregation state can modify its activity and pharmacokinetical characteristics. In spite of its …

Cutaneous leishmaniasis treatment

P Minodier, P Parola - Travel medicine and infectious disease, 2007 - Elsevier
The causative species of cutaneous leishmaniasis determines the clinical features and
courses, and treatments. Intralesional or systemic antimonials are the gold standard for the …