HMGB1 in health and disease

R Kang, R Chen, Q Zhang, W Hou, S Wu, L Cao… - Molecular aspects of …, 2014‏ - Elsevier
Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

Inflammatory response in islet transplantation

MA Kanak, M Takita, F Kunnathodi… - International journal …, 2014‏ - Wiley Online Library
Islet cell transplantation is a promising beta cell replacement therapy for patients with brittle
type 1 diabetes as well as refractory chronic pancreatitis. Despite the vast advancements …

[HTML][HTML] Evidence for instant blood-mediated inflammatory reaction in clinical autologous islet transplantation

B Naziruddin, S Iwahashi, MA Kanak, M Takita… - American Journal of …, 2014‏ - Elsevier
A nonspecific inflammatory and thrombotic reaction termed instant blood-mediated
inflammatory reaction (IBMIR) has been reported when allogenic or xenogenic islets come …

The role of HMGB1 in the pathogenesis of type 2 diabetes

Y Wang, J Zhong, X Zhang, Z Liu… - Journal of diabetes …, 2016‏ - Wiley Online Library
Significance. With an alarming increase in recent years, diabetes mellitus has become a
global challenge. Despite advances in treatment of diabetes mellitus, currently, medications …

Inflammatory triggers of acute rejection of organ allografts

DN Mori, D Kreisel, JN Fullerton, DW Gilroy… - Immunological …, 2014‏ - Wiley Online Library
Solid organ transplantation is a vital therapy for end stage diseases. Decades of research
have established that components of the adaptive immune system are critical for transplant …

Progress in clinical encapsulated islet xenotransplantation

DKC Cooper, S Matsumoto, A Abalovich, T Itoh… - …, 2016‏ - journals.lww.com
At the 2015 combined congress of the Cell Transplant Society, International Pancreas and
Islet Transplant Association, and International Xenotransplantation Association, a …

Anti-inflammatory strategies to enhance islet engraftment and survival

A Citro, E Cantarelli, L Piemonti - Current diabetes reports, 2013‏ - Springer
Early innate inflammatory reaction strongly affects islet engraftment and survival after
intrahepatic transplantation. This early immune response is triggered by ischemia …

Regulated cell death seen through the lens of islet transplantation

A Bruni, S Bornstein, A Linkermann… - Cell …, 2018‏ - journals.sagepub.com
Clinical islet transplantation effectively restores euglycemia and corrects glycosylated
hemoglobin in labile type 1 diabetes mellitus (T1DM). Despite marked improvements in islet …

Immunothrombotic activity of damage-associated molecular patterns and extracellular vesicles in secondary organ failure induced by trauma and sterile insults

J Eppensteiner, RP Davis, AS Barbas, J Kwun… - Frontiers in …, 2018‏ - frontiersin.org
Despite significant improvements in injury prevention and emergency response, injury-
related death and morbidity continues to increase in the US and worldwide. Patients with …

Associations of insulin sensitivity and immune inflammatory responses with child blood lead (Pb) and PM2.5 exposure at an e-waste recycling area during the COVID …

X Zheng, Q Wang, X Xu, X Huang, J Chen… - … geochemistry and health, 2024‏ - Springer
Abstract Fine particular matter (PM2. 5) and lead (Pb) exposure can induce insulin
resistance, elevating the likelihood of diabetes onset. Nonetheless, the underlying …