Bone defects are among the most common damages in human medicine. Due to limitations
and challenges in the area of bone healing, the research field has turned into a hot topic …

Osteochondral tissue (OCT) related diseases, particularly osteoarthritis, number among the
most prevalent in the adult population worldwide. However, no satisfactory clinical …

This study aimed to improve the mechanical and biological properties of alginate-based
hydrogels. For this purpose, in-situ forming hydrogels were prepared by dual crosslinking of …

Muscular diseases and injuries are challenging issues in human medicine, resulting in
physical disability. The advent of tissue engineering approaches has paved the way for the …

Mimicking the natural bone extracellular matrix containing intrinsic topography and electrical
signals is an effective way to modulate bone regeneration. However, simultaneously …

Osteoporosis is a common bone and metabolic disease that is characterized by bone
density loss and microstructural degeneration. Human bone marrow-derived mesenchymal …

Recent advancements in tissue engineering have demonstrated a great potential for the
fabrication of three-dimensional (3D) tissue structures such as cartilage and bone. However …

Long non-coding RNAs (lncRNA) are non-protein coding RNA molecules that are longer
than 200 nucleotides. The lncRNA molecule plays diverse roles in gene regulation …

Abnormal craniofacial bone fusion can lead to the generation of several congenital
malformations such as cleft palate, craniosynostosis and craniofacial skeletal hypoplasia …

Human mesenchymal stem cells (hMSCs) have great potential in cell-based therapies for
tissue engineering and regenerative medicine due to their self-renewal and multipotent …