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HIF1A gene polymorphisms and human diseases: Graphical review of 97 association studies
Hypoxia‐inducible factors (HIFs) belong to a family of transcription factors (TF) responsive to
a low O2 availability, which is often a characteristic feature of solid tumors. The alpha …
a low O2 availability, which is often a characteristic feature of solid tumors. The alpha …
[HTML][HTML] In vitro antimicrobial and anticancer potential of hinokitiol against oral pathogens and oral cancer cell lines
Hinokitiol is a natural component isolated from Chamacyparis taiwanensis. It has anti-
microbial activity, and has been used in oral care products. The minimal inhibitory …
microbial activity, and has been used in oral care products. The minimal inhibitory …
The association between HIF-1α polymorphism and cancer risk: a systematic review and meta-analysis
X Hu, Y Fang, J Zheng, Y He, X Zan, S Lin, X Li, H Li… - Tumor Biology, 2014 - Springer
Epidemiological studies have assessed the association between HIF-1α polymorphisms and
cancer risk. However, the results remained conflicting rather than conclusive. Therefore, we …
cancer risk. However, the results remained conflicting rather than conclusive. Therefore, we …
Evaluation Physical Characteristics and Comparison Antimicrobial and Anti-Inflammation Potentials of Dental Root Canal Sealers Containing Hinokitiol In Vitro
Hinokitiol displays potent antimicrobial activity. It has been used in toothpaste and oral-care
gel to improve the oral lichen planus and reduce halitosis. The aim of this study was to …
gel to improve the oral lichen planus and reduce halitosis. The aim of this study was to …
Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia‐telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous …
SM Hsia, CC Yu, YH Shih, M Yuanchien Chen… - Head & …, 2016 - Wiley Online Library
Background Isoliquiritigenin (ISL), a natural compound extracted from licorice, has
chemopreventive and antitumor activities. The purpose of this study was to investigate the …
chemopreventive and antitumor activities. The purpose of this study was to investigate the …
Genetic polymorphisms in HIF1A are associated with prostate cancer risk in a Chinese population
P Li, Q Cao, PF Shao, HZ Cai, H Zhou… - Asian journal of …, 2012 - pmc.ncbi.nlm.nih.gov
The hypoxia-inducible factor-1α (HIF-1α) plays an important role in regulating angiogenesis,
which is essential for tumor growth and metastasis. Genetic variations of HIF1A (coding HIF …
which is essential for tumor growth and metastasis. Genetic variations of HIF1A (coding HIF …
Lysyl oxidase and enhancement of cell proliferation and angiogenesis in oral squamous cell carcinoma
Background Lysyl oxidase (LOX) is a copper‐dependent enzyme that cross‐links collagen
and elastin in the extracellular matrix. LOX overexpressed in various tumors. The manner in …
and elastin in the extracellular matrix. LOX overexpressed in various tumors. The manner in …
A meta-analysis of hypoxia inducible factor 1-alpha (HIF1A) gene polymorphisms: association with cancers
Background Hypoxia inducible factor 1-alpha (HIF1A) is a transcription factor that plays
important role in regulating cascade of reactions. In this study, the effect of rs11549465 …
important role in regulating cascade of reactions. In this study, the effect of rs11549465 …
Clinicopathological characteristics of gynecological cancer associated with hypoxia-inducible factor 1α expression: a meta-analysis including 6,612 subjects
Y **, H Wang, X Ma, X Liang, X Liu, Y Wang - PloS one, 2015 - journals.plos.org
Background Gynecological cancer is characterized by tumor hypoxia. However, the role of
hypoxia-inducible factor 1α (HIF-1α) in gynecological cancer remains unclear. Method …
hypoxia-inducible factor 1α (HIF-1α) in gynecological cancer remains unclear. Method …
Association between HIF-1α C1772T/G1790A polymorphisms and cancer susceptibility: an updated systematic review and meta-analysis based on 40 case-control …
Q Yan, P Chen, S Wang, N Liu, P Zhao, A Gu - BMC cancer, 2014 - Springer
Abstract Background HIF-1 (hypoxia-inducible factor 1) is a transcriptional activator that
functions as a critical regulator of oxygen homeostasis. Recently, a large number of …
functions as a critical regulator of oxygen homeostasis. Recently, a large number of …