Physical exercise and its protective effects on diabetic cardiomyopathy: What is the evidence?

J Zheng, J Cheng, S Zheng, L Zhang, X Guo… - Frontiers in …, 2018 - frontiersin.org
As one of the most serious complications of diabetes, diabetic cardiomyopathy (DCM)
imposes a huge burden on individuals and society, and represents a major public health …

[HTML][HTML] Exercise as a potential therapeutic target for diabetic cardiomyopathy: insight into the underlying mechanisms

DY Seo, JR Ko, JE Jang, TN Kim, JB Youm… - International journal of …, 2019 - mdpi.com
Diabetes mellitus is associated with cardiovascular, ophthalmic, and renal comorbidities.
Among these, diabetic cardiomyopathy (DCM) causes the most severe symptoms and is …

ATP releasing channels and the ameliorative effects of high intensity interval training on diabetic heart: a multifaceted analysis

S Joukar, MA Rajizadeh, MA Bejeshk, SS Alavi… - Scientific Reports, 2024 - nature.com
Abstract Type 2 diabetes (T2D) can cause severe cardiac complications at functional,
histologic and molecular levels. These pathological complications could be mediated by …

[HTML][HTML] Moderate-and high-intensity endurance training alleviate diabetes-induced cardiac dysfunction in rats

S D'Haese, M Verboven, L Evens, D Deluyker… - Nutrients, 2023 - mdpi.com
Exercise training is an encouraging approach to treat cardiac dysfunction in type 2 diabetes
(T2DM), but the impact of its intensity is not understood. We aim to investigate whether and …

Involvement of sirtuins and klotho in cardioprotective effects of exercise training against waterpipe tobacco smoking-induced heart dysfunction

SS Alavi, S Joukar, F Rostamzadeh… - Frontiers in …, 2021 - frontiersin.org
Despite its negative effect on the cardiovascular system, waterpipe smoking (WPS) is
currently popular worldwide, especially among youth. This study investigated the effects of …

High-intensity interval training reversed high-fat diet–induced M1-macrophage polarization in rat adipose tissue via inhibition of NOTCH signaling

M Shanaki, M Khosravi… - Journal of …, 2020 - Taylor & Francis
Introduction There is accumulating evidence on the beneficial effect of exercise intervention
in the management of metabolic disorders; however, the molecular mechanism is still …

Moderate-intensity and high-intensity interval exercise training offer equal cardioprotection, with different mechanisms, during the development of type 2 diabetes in …

S D'Haese, L Claes, I de Laat, S Van Campenhout… - Nutrients, 2024 - mdpi.com
Endurance exercise training is a promising cardioprotective strategy in type 2 diabetes
mellitus (T2DM), but the impact of its intensity is not clear. We aimed to investigate whether …

Effects of two workload-matched high intensity interval training protocols on regulatory factors associated with mitochondrial biogenesis in the soleus muscle of …

M Delfan, A Vahed, DJ Bishop… - Frontiers in …, 2022 - frontiersin.org
Aims: High intensity interval training (HIIT) improves mitochondrial characteristics. This study
compared the impact of two workload-matched high intensity interval training (HIIT) …

High intensity interval training improves diabetic cardiomyopathy via miR-1 dependent suppression of cardiomyocyte apoptosis in diabetic rats

M Delfan, M Delphan, MR Kordi, AA Ravasi… - Journal of Diabetes & …, 2020 - Springer
Purpose Diabetes and its complications such as diabetic cardiomyopathy still account for
significant morbidity and mortality. High-quality evidence was shown the importance of …

The effect of high intensity interval training on FOXO3, PI3K and AKT proteins content in heart muscle of type two diabetic rats

M Rami, S Rahdar, M Azimpour… - Journal of Practical …, 2023 - jpsbs.birjand.ac.ir
Background and Aim: Diabetes can causes disturbances in glucose homeostasis and
negative changes in the heart muscle. Since physical activity in people with diabetes may …