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[HTML][HTML] DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …
population-based cancer screening methods remain an unmet need, since cancer detection …
Epidemiology of lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines
Background Ever since a lung cancer epidemic emerged in the mid-1900s, the
epidemiology of lung cancer has been intensively investigated to characterize its causes …
epidemiology of lung cancer has been intensively investigated to characterize its causes …
Lung cancer epigenetics: from knowledge to applications
Lung cancer is the leading cause of cancer-related mortality worldwide. Advances in our
understanding of the genomics of lung cancer have led to substantial progress in the …
understanding of the genomics of lung cancer have led to substantial progress in the …
Early detection of lung cancer using DNA promoter hypermethylation in plasma and sputum
Purpose: CT screening can reduce death from lung cancer. We sought to improve the
diagnostic accuracy of lung cancer screening using ultrasensitive methods and a lung …
diagnostic accuracy of lung cancer screening using ultrasensitive methods and a lung …
Potential clinical utility of liquid biopsy in early-stage non-small cell lung cancer
H Shen, Y **, H Zhao, M Wu, K Zhang, Z Wei, X Wang… - BMC medicine, 2022 - Springer
Background Liquid biopsy has been widely researched for early diagnosis, prognostication
and disease monitoring in lung cancer, but there is a need to investigate its clinical utility for …
and disease monitoring in lung cancer, but there is a need to investigate its clinical utility for …
Kinesins and cancer
O Rath, F Kozielski - Nature reviews cancer, 2012 - nature.com
Kinesins are a family of molecular motors that travel unidirectionally along microtubule
tracks to fulfil their many roles in intracellular transport or cell division. Over the past few …
tracks to fulfil their many roles in intracellular transport or cell division. Over the past few …
Methylation of cell-free circulating DNA in the diagnosis of cancer
K Warton, G Samimi - Frontiers in molecular biosciences, 2015 - frontiersin.org
A range of molecular alterations found in tumor cells, such as DNA mutations and DNA
methylation, is reflected in cell-free circulating DNA (circDNA) released from the tumor into …
methylation, is reflected in cell-free circulating DNA (circDNA) released from the tumor into …
[HTML][HTML] Cancer epigenetic biomarkers in liquid biopsy for high incidence malignancies
C Palanca-Ballester, A Rodriguez-Casanova, S Torres… - Cancers, 2021 - mdpi.com
Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …
Diagnosis of lung cancer in individuals with solitary pulmonary nodules by plasma microRNA biomarkers
Background Making a definitive preoperative diagnosis of solitary pulmonary nodules
(SPNs) found by CT has been a clinical challenge. We previously demonstrated that …
(SPNs) found by CT has been a clinical challenge. We previously demonstrated that …
Detection of promoter DNA methylation in urine and plasma aids the detection of non–small cell lung cancer
Purpose: Low-dose CT screening can reduce lung cancer–related mortality. However, CT
screening has an FDR of nearly 96%. We sought to assess whether urine samples can be a …
screening has an FDR of nearly 96%. We sought to assess whether urine samples can be a …