Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging
technique that enables in vivo reconstruction of the brain's white matter connections at …

Deep brain stimulation (DBS) is a highly efficacious treatment option for movement disorders
and a growing number of other indications are investigated in clinical trials. To ensure …

Parkinson's disease (PD) is characterised by the emergence of beta frequency oscillatory
synchronisation across the cortico-basal-ganglia circuit. The relationship between the …

Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …

Multiple surgical targets for treating obsessive-compulsive disorder with deep brain
stimulation (DBS) have been proposed. However, different targets may modulate the same …

The process of altering neural activity–neuromodulation–has long been used to treat
patients with brain disorders and answer scientific questions. Deep brain stimulation in …

Deep brain stimulation (DBS) of 3 different targets is the most important therapeutic
innovation of the past 30 years for patients with fluctuating Parkinson's disease (PD) …

Objective To investigate whether functional sweet spots of deep brain stimulation (DBS) in
the subthalamic nucleus (STN) can predict motor improvement in Parkinson disease (PD) …

Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …