The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy
Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …
Ultrasound-based micro-/nanosystems for biomedical applications
H Huang, Y Zheng, M Chang, J Song, L **a… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …
Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy
H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …
Conquering the hypoxia limitation for photodynamic therapy
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
Acceptor Planarization and Donor Rotation: A Facile Strategy for Realizing Synergistic Cancer Phototherapy via Type I PDT and PTT
L Feng, C Li, L Liu, Z Wang, Z Chen, J Yu, W Ji… - ACS …, 2022 - ACS Publications
Tumor hypoxia seriously impairs the therapeutic outcomes of type II photodynamic therapy
(PDT), which is highly dependent upon tissue oxygen concentration. Herein, a facile strategy …
(PDT), which is highly dependent upon tissue oxygen concentration. Herein, a facile strategy …
In situ hypoxia-induced supramolecular perylene diimide radical anions in tumors for photothermal therapy with improved specificity
H Wang, KF Xue, Y Yang, H Hu, JF Xu… - Journal of the American …, 2022 - ACS Publications
Considering that hypoxia is closely associated with tumor proliferation, invasion, metastasis,
and drug resistance, it is of great significance to overcome hypoxia in tumor treatment …
and drug resistance, it is of great significance to overcome hypoxia in tumor treatment …
Chemical design of activatable photoacoustic probes for precise biomedical applications
Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …
integrates the advantage of optical and acoustic imaging, has great application prospects in …
Biodegradable NIR‐II Pseudo Conjugate Polymeric Nanoparticles Amplify Photodynamic Immunotherapy via Alleviation of Tumor Hypoxia and Tumor‐Associated …
J Wan, X Zhang, D Tang, T Liu, H **ao - Advanced Materials, 2023 - Wiley Online Library
Photodynamic therapy (PDT) has achieved great success in cancer treatment. Despite its
great promise, the efficacy of photodynamic immunotherapy can be limited by the hypoxia in …
great promise, the efficacy of photodynamic immunotherapy can be limited by the hypoxia in …
Efficient NIR-II type-I AIE photosensitizer for mitochondria-targeted photodynamic therapy through synergistic apoptosis–ferroptosis
J Zhuang, B Wang, H Chen, K Zhang, N Li, N Zhao… - ACS …, 2023 - ACS Publications
Hypoxia, the hallmark of malignant tumors, has been recognized as a major obstacle for
photodynamic therapy (PDT). Precisely targeting cancer cells in intricate biological …
photodynamic therapy (PDT). Precisely targeting cancer cells in intricate biological …
[HTML][HTML] Fluorescent-based nanosensors for selective detection of a wide range of biological macromolecules: A comprehensive review
Thanks to their unique attributes, such as good sensitivity, selectivity, high surface-to-volume
ratio, and versatile optical and electronic properties, fluorescent-based bioprobes have been …
ratio, and versatile optical and electronic properties, fluorescent-based bioprobes have been …