Medicinal applications of vanadium complexes with Schiff bases

K Hashmi, S Gupta, A Siddique, T Khan… - Journal of Trace Elements …, 2023 - Elsevier
Many transition metal complexes have been explored for their therapeutic properties after
the discovery of cisplatin. Schiff bases have an efficient complexation tendency with the …

[PDF][PDF] Biochemical and medical importance of vanadium compounds

J Korbecki, I Baranowska-Bosiacka… - Acta Biochimica …, 2012 - frontierspartnerships.org
Vanadium belongs to the group of transition metals and is present in the air and soil
contaminants in large urban agglomerations due to combustion of fossil fuels. It forms …

Vanadium in the detection, prevention and treatment of cancer: the in vivo evidence

A Bishayee, A Waghray, MA Patel, M Chatterjee - Cancer Letters, 2010 - Elsevier
Vanadium, a dietary micronutrient, is yet to be established as an essential part of the human
diet. Over the past century, several biological effects of vanadium, such as insulin-mimetic …

Stabilities and biological activities of vanadium drugs: what is the nature of the active species?

A Levina, PA Lay - Chemistry–An Asian Journal, 2017 - Wiley Online Library
Diverse biological activities of vanadium (V) drugs mainly arise from their abilities to inhibit
phosphatase enzymes and to alter cell signaling. Initial interest focused on anti‐diabetic …

Vanadium dioxide nanocoating induces tumor cell death through mitochondrial electron transport chain interruption

J Li, M Jiang, H Zhou, P **, KMC Cheung… - Global …, 2019 - Wiley Online Library
A biomaterials surface enabling the induction of tumor cell death is particularly desirable for
implantable biomedical devices that directly contact tumor tissues. However, this specific …

Potential use of vanadium compounds in therapeutics

D A. Barrio, S B. Etcheverry - Current medicinal chemistry, 2010 - benthamdirect.com
Vanadium is a trace element present in practically all cells in plants and animals. While the
essentiality of vanadium for human beings remains to be well established, vanadium has …

Revisiting prostate cancer metabolism: From metabolites to disease and therapy

HJ Cardoso, TMA Carvalho… - Medicinal Research …, 2021 - Wiley Online Library
Prostate cancer (PCa), one of the most commonly diagnosed cancers worldwide, still
presents important unmet clinical needs concerning treatment. In the last years, the …

Synthesis and characterization of unsymmetrical oxidovanadium complexes: DNA-binding, cleavage studies and antitumor activities

J Lu, H Guo, X Zeng, Y Zhang, P Zhao, J Jiang… - Journal of inorganic …, 2012 - Elsevier
Four oxidovanadium (IV) complexes,[VO (hntdtsc)(phen)](1),[VO (hntdtsc)(bpy)](2)(hntdtsc=
2-hydroxy-1-naphthaldehyde thiosemicarbazone, phen= 1, 10-phenanthroline),[VO …

Cu (II) and V (IV) O complexes with tri-or tetradentate ligands based on (2-hydroxybenzyl)-L-alanines reveal promising anticancer therapeutic potential

N Ribeiro, I Bulut, B Cevatemre, C Teixeira… - Dalton …, 2021 - pubs.rsc.org
Four new ligand precursors (H2L1–H2L4), derived from the Mannich condensation of two
amino acids (L-Val and L-Phe) and two 3, 5-disubstituted phenols (t-Bu or Me), and the …

Sodium orthovanadate inhibits growth of human hepatocellular carcinoma cells in vitro and in an orthotopic model in vivo

Y Wu, Y Ma, Z Xu, D Wang, B Zhao, H Pan, J Wang… - Cancer letters, 2014 - Elsevier
The transition metal vanadium is widely distributed in the environment and exhibits various
biological and physiological effects in the human body. As a well known vanadium …