The carbamate group is a key structural motif in many approved drugs and prodrugs. There
is an increasing use of carbamates in medicinal chemistry and many derivatives are …

Environmentally friendly products and procedures are being developed both in industry and
academia, mainly due to the depletion of fossil resources and the growing global awareness …

The urea functionality is inherent to numerous bioactive compounds, including a variety of
clinically approved therapies. Urea containing compounds are increasingly used in …

Mechanistic investigations on the Cp* Rh (III)-catalyzed direct C–H amination reaction led us
to reveal the new utility of 1, 4, 2-dioxazol-5-one and its derivatives as highly efficient amino …

Dioxazolones are a convenient class of acyl nitrene transfer reagents. Their application in
homogeneous transition-metal catalysis has led to many new amidation reactions …

N–N linkages are found in many natural compounds and endow fascinating structural and
functional properties. In comparison to the myriad methods for the construction of C–N …

Herein, visible‐light‐driven iron‐catalyzed nitrene transfer reactions with dioxazolones for
intermolecular C (sp3)‐N, N= S, and N= P bond formation are described. These reactions …

An efficient method for intermolecular branch-selective allylic C–H amidation has been
accomplished via Ir (III) catalysis. The reaction proceeds through initial allylic C–H activation …

Hydroxamate‐based histone deacetylase inhibitors (HDACIs) have been approved as
therapeutic agents by the US Food and Drug Administration for use in oncology …

Nitrogenation by direct functionalization of C H bonds represents an important strategy for
constructing C N bonds. Rhodium (III)‐catalyzed direct amidation of unactivated C (sp3) …