Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …

Fungi have the capability to produce a tremendous number of so-called secondary
metabolites, which possess a multitude of functions, eg, communication signals during …

Metals are essential for life, and they play a central role in the struggle between infecting
microbes and their hosts. In fact, an important aspect of microbial pathogenesis is the …

To maintain iron homeostasis, fungi have to balance iron acquisition, storage, and utilization
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …

Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe
infections with invasive growth in immunocompromised patients. The fungal cell wall (CW) …

Production of many crops, including bananas, is threatened worldwide by the spread of
pathogenic strains of Fusarium oxysporum, the causal agent of Fusarium wilt. Severity of the …

Pseudomonas aeruginosa and Aspergillus fumigatus are common opportunistic bacterial
and fungal pathogens, respectively. They often coexist in airways of immunocompromised …

Yeast adaptation to stress has been extensively studied. It involves large reprogramming of
genome expression operated by many, more or less specific, transcription factors. Here, we …

Azole drugs selectively target fungal sterol biosynthesis and are critical to our antifungal
therapeutic arsenal. However, resistance to this class of drugs, particularly in the major …

The opportunistic fungal pathogen Aspergillus fumigatus utilizes two high-affinity iron uptake
mechanisms, termed reductive iron assimilation (RIA) and siderophore-mediated iron …