sarcopenia in cirrhosis–aetiology, implications and potential therapeutic interventions

M Sinclair, PJ Gow, M Grossmann… - Alimentary …, 2016 - Wiley Online Library
Background Sarcopenia (loss of muscle mass) is common in cirrhosis and is associated with
poor outcomes. Current teaching recommends the use of protein supplementation and …

Pathogenesis of hepatic encephalopathy: role of ammonia and systemic inflammation

DR Aldridge, EJ Tranah, DL Shawcross - Journal of clinical and …, 2015 - Elsevier
The syndrome we refer to as Hepatic Encephalopathy (HE) was first characterized by a team
of Nobel Prize winning physiologists led by Pavlov and Nencki at the Imperial Institute of …

Covert and overt hepatic encephalopathy: diagnosis and management

KR Patidar, JS Bajaj - Clinical Gastroenterology and Hepatology, 2015 - Elsevier
Hepatic encephalopathy (HE) is part of a spectrum of neurocognitive changes in cirrhosis.
HE is divided into 2 broad categories based on severity: covert hepatic encephalopathy …

[PDF][PDF] Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis

Q Liu, ZP Duan, DK Ha, S Bengmark, J Kurtovic… - …, 2004 - Wiley Online Library
Minimal hepatic encephalopathy (MHE) is an important disorder that may seriously impair
daily functioning and quality of life in patients with cirrhosis. Treatment with lactulose is of …

[PDF][PDF] Lactulose improves cognitive functions and health‐related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy

S Prasad, RK Dhiman, A Duseja, YK Chawla… - …, 2007 - Wiley Online Library
Minimal hepatic encephalopathy (MHE) has a negative effect on patients' daily functioning.
Thus far, no study has investigated the effect of treatment‐related improvement in cognitive …

the design of clinical trials in hepatic encephalopathy–an International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) consensus statement

JS Bajaj, J Cordoba, KD Mullen… - Alimentary …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 33: 739–747 Summary Background The clinical classification
of hepatic encephalopathy is largely subjective, which has led to difficulties in designing …

Secondary prophylaxis of hepatic encephalopathy: an open-label randomized controlled trial of lactulose versus placebo

BC Sharma, P Sharma, A Agrawal, SK Sarin - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Hepatic encephalopathy (HE) is associated with a poor prognosis.
Lactulose is used for the treatment of HE. There is no study on the prevention of recurrence …

The burden of hepatic encephalopathy

FF Poordad - Alimentary pharmacology & therapeutics, 2007 - Wiley Online Library
Hepatic encephalopathy, a challenging complication of advanced liver disease, occurs in
approximately 30–45% of patients with cirrhosis and 10–50% of patients with transjugular …

[SÁCH][B] Hepatology Principles and Practice: History· Morphology Biochemistry· Diagnostics Clinic· Therapy

E Kuntz - 2006 - Springer
Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

[PDF][PDF] Value of the critical flicker frequency in patients with minimal hepatic encephalopathy

M Romero‐Gómez, J Córdoba, R Jover… - …, 2007 - Wiley Online Library
Minimal hepatic encephalopathy (MHE) is mainly diagnosed using psychometric tests such
as the psychometric hepatic encephalopathy score (PHES). Despite the clinical and social …