Force steadiness: from motor units to voluntary actions

RM Enoka, D Farina - Physiology, 2021 - journals.physiology.org
Voluntary actions are controlled by the synaptic inputs that are shared by pools of spinal
motor neurons. The slow common oscillations in the discharge times of motor units due to …

The pathophysiology of motor fatigue and fatigability in multiple sclerosis

R Patejdl, UK Zettl - Frontiers in Neurology, 2022 - frontiersin.org
Multiple Sclerosis (MS) is a heterogeneous immune mediated disease of the central nervous
system (CNS). Fatigue is one of the most common and disabling symptom of MS. It interferes …

Distinguishing between fatigue and fatigability in multiple sclerosis

RM Enoka, AM Almuklass, M Alenazy… - … and Neural Repair, 2021 - journals.sagepub.com
Fatigue is one of the most common debilitating symptoms reported by persons with multiple
sclerosis (MS). It reflects feelings of tiredness, lack of energy, low motivation, and difficulty in …

Force control during submaximal isometric contractions is associated with walking performance in persons with multiple sclerosis

LA Davis, MS Alenazy, AM Almuklass… - Journal of …, 2020 - journals.physiology.org
Individuals with multiple sclerosis (MS) experience progressive declines in movement
capabilities, especially walking performance. The purpose of our study was to compare the …

The role of remote monitoring in evaluating fatigue in multiple sclerosis: a review

VJ Block, R Bove, B Nourbakhsh - Frontiers in Neurology, 2022 - frontiersin.org
Fatigue is one of the most common multiple sclerosis (MS) symptoms. Despite this,
monitoring and measuring fatigue (subjective lack of energy)–and fatigability (objectively …

Fatigability and the role of neuromuscular impairments in chronic kidney disease

JM Gollie, SS Patel, MO Harris-Love… - American journal of …, 2022 - karger.com
Background: The combination of neuromuscular impairments plus psychosocial aspects of
chronic kidney disease (CKD) may predispose these patients to greater risk for experiencing …

Cognitive challenge as a probe to expose sex-and age-related differences during static contractions

HM Pereira, SK Hunter - Frontiers in Physiology, 2023 - frontiersin.org
Despite activities of daily living being frequently performed simultaneously with a cognitive
task, motor function is often investigated in isolation, which can hinder the applicability of …

Upper and lower limb performance fatigability in people with multiple sclerosis investigated through surface electromyography: a pilot study

M Beretta-Piccoli, C Cescon, M Barbero… - Physiological …, 2020 - iopscience.iop.org
Objective: Fatigue experienced by people with multiple sclerosis (pwMS) is
multidimensional, consisting of different components, such as perceived, physical and …

People with multiple sclerosis have reduced TMS-evoked motor cortical output compared with healthy individuals during fatiguing submaximal contractions

EJ Brotherton, S Sabapathy… - Journal of …, 2022 - journals.physiology.org
People with multiple sclerosis (PwMS) typically experience greater levels of exercise-
induced fatigue compared with healthy individuals. Therefore, this study examined …

Hand fatigability, self-reported fatigue, and functionality in individuals with multiple sclerosis: A cross-sectional study

D Simsek, N Cetisli-Korkmaz, LS Bir - Multiple sclerosis and related …, 2024 - Elsevier
Background The individual experience of fatigue and fatigability in individuals with Multiple
Sclerosis (MS) can vary greatly, beyond the high prevalence of fatigue in MS. Although …