Nitrotyrosine, nitrated lipoproteins, and cardiovascular dysfunction in patients with type 2 diabetes: What do we know and what remains to be explained?

GK Jakubiak, G Cieślar, A Stanek - Antioxidants, 2022 - mdpi.com
Diabetes mellitus (DM) is a strong risk factor for the development of cardiovascular diseases
(CVDs), which are the most important cause of morbidity and mortality in the population of …

A systematic review and meta-analysis of the effect of statins on glutathione peroxidase, superoxide dismutase, and catalase

A Zinellu, AA Mangoni - Antioxidants, 2021 - mdpi.com
Statins may exert protective effects against oxidative stress by upregulating specific
antioxidant mechanisms. We conducted a systematic review and meta-analysis of the effect …

Analysis of the mechanism of action of quercetin in the treatment of hyperlipidemia based on metabolomics and intestinal flora

T Wang, L Liu, J Deng, Y Jiang, X Yan, W Liu - Food & function, 2023 - pubs.rsc.org
Hyperlipidemia (HLP) is one of the main factors leading to cardiovascular diseases.
Quercetin (QUE) is a naturally occurring polyhydroxy flavonoid compound that has a wide …

The relationship of redox signaling with the risk for atherosclerosis

S Lei, C Liu, T Zheng, W Fu, M Huang - Frontiers in Pharmacology, 2024 - frontiersin.org
Oxidative balance plays a pivotal role in physiological homeostasis, and many diseases,
particularly age-related conditions, are closely associated with oxidative imbalance. While …

Atheroprotective role of vinpocetine: an old drug with new indication

MH Abu-Alghayth, HM Al-Kuraishy, AI Al-Gareeb… - …, 2024 - Springer
Endothelial dysfunction is considered one of the main causes of atherosclerosis and
elevated blood pressure. Atherosclerosis (AS) formation is enhanced by different …

Puerarin alleviates coronary heart disease via suppressing inflammation in a rat model

L Zhao, L Wang, D Zhang, Y Chen, F ** - Gene, 2021 - Elsevier
Background Puerarin shows inhibitory effects on inflammation in chronic heart failure (CHF),
but its efficacy in coronary heart disease (CHD) remained vague. Methods Rat CHD model …

Biological markers of oxidative stress in cardiovascular diseases: after so many studies, what do we know?

J Fontana, M Zima, V Vetvicka - Immunological Investigations, 2018 - Taylor & Francis
Numerous conditions, including cancer, diabetes, aging, and atherosclerosis, are thought to
be associated with oxidative stress. Oxidative stress is defined as a persistent imbalance …

Hsa_circ_0004831 downregulation is partially responsible for atorvastatinalleviated human umbilical vein endothelial cell injuries induced by ox-LDL through …

G Su, G Sun, J Lv, W Zhang, H Liu, Y Tang… - BMC Cardiovascular …, 2021 - Springer
Background The dysfunction and injury of human umbilical vein endothelial cells (HUVECs)
are key events of atherosclerosis (AS). Atorvastatin (ATV) has been shown to play a …

Evaluating Plasma Galectin-3 Levels in Patients With an Increased Risk of Atherosclerotic Cardiovascular Disease Who Underwent Coronary Artery Revascularization

F Mayyas, K Ibrahim - The American Journal of Cardiology, 2023 - Elsevier
Coronary artery disease (CAD) is a common atherosclerotic cardiovascular disease
(ASCVD) associated with significant mortality. Galectin-3 is a novel inflammatory factor …

Cardiac effects of cigarette tobacco smoking in rat model of diabetes

F Mayyas, KH Alzoubi - Life sciences, 2018 - Elsevier
Aims Tobacco smoking is considered a global health issue, contributing to increased risk of
cardiovascular disease (CVD) and diabetes (DM). We aimed to assess effects of cigarette …