Extracellular matrix-derived biomaterials in engineering cell function

H **ng, H Lee, L Luo, TR Kyriakides - Biotechnology advances, 2020 - Elsevier
Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

The bioactivity of cartilage extracellular matrix in articular cartilage regeneration

AJ Sutherland, GL Converse… - Advanced …, 2015 - Wiley Online Library
Cartilage matrix is a promising material for cartilage regeneration given the evidence
supporting its chondroinductive character. The “raw materials” of cartilage matrix can serve …

Successful endothelialization and remodeling of a cell-free small-diameter arterial graft in a large animal model

MT Koobatian, S Row, RJ Smith Jr, C Koenigsknecht… - Biomaterials, 2016 - Elsevier
The large number of coronary artery bypass procedures necessitates development of off-the-
shelf vascular grafts that do not require cell or tissue harvest from patients. However …

Small intestinal submucosa: superiority, limitations and solutions, and its potential to address bottlenecks in tissue repair

G Cao, Y Huang, K Li, Y Fan, H **e, X Li - Journal of Materials …, 2019 - pubs.rsc.org
Over the past few decades, small intestinal submucosa (SIS), a naturally occurring
decellularized extracellular matrix (ECM), has attracted much attention in tissue repair …

Towards stem cell therapies for skeletal muscle repair

RN Judson, FMV Rossi - NPJ Regenerative medicine, 2020 - nature.com
Skeletal muscle is an ideal target for cell therapy. The use of its potent stem cell population
in the form of autologous intramuscular transplantation represents a tantalizing strategy to …

Topical collagen-based biomaterials for chronic wounds: rationale and clinical application

LJ Gould - Advances in wound care, 2016 - liebertpub.com
Significance: The extracellular matrix (ECM) is known to be deficient in chronic wounds.
Collagen is the major protein in the ECM. Many claims are made while extolling the virtues …

[HTML][HTML] Decellularized scaffolds in regenerative medicine

Y Yu, A Alkhawaji, Y Ding, J Mei - Oncotarget, 2016 - ncbi.nlm.nih.gov
Allogeneic organ transplantation remains the ultimate solution for end-stage organ failure.
Yet, the clinical application is limited by the shortage of donor organs and the need for …

Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder

F Ajalloueian, G Lemon, J Hilborn, IS Chronakis… - Nature Reviews …, 2018 - nature.com
The urinary bladder is a complex organ with the primary functions of storing urine under low
and stable pressure and micturition. Many clinical conditions can cause poor bladder …

Interactions between skeletal muscle myoblasts and their extracellular matrix revealed by a serum free culture system

V Chaturvedi, DE Dye, BF Kinnear, TH Van Kuppevelt… - PloS one, 2015 - journals.plos.org
Decellularisation of skeletal muscle provides a system to study the interactions of myoblasts
with muscle extracellular matrix (ECM). This study describes the efficient decellularisation of …

Regenerative medicine: charting a new course in wound healing

GC Gurtner, MA Chapman - Advances in wound care, 2016 - liebertpub.com
Significance: Chronic wounds are a prevalent and costly problem in the United States.
Improved treatments are needed to heal these wounds and prevent serious complications …