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Genetic dissection of complex traits
ES Lander, NJ Schork - Focus, 2006 - psychiatryonline.org
Medical genetics was revolutionized during the 1980s by the application of genetic map**
to locate the genes responsible for simple Mendelian diseases. Most diseases and traits …
to locate the genes responsible for simple Mendelian diseases. Most diseases and traits …
Map** and analysis of quantitative trait loci in experimental populations
RW Doerge - Nature Reviews Genetics, 2002 - nature.com
Simple statistical methods for the study of quantitative trait loci (QTL), such as analysis of
variance, have given way to methods that involve several markers and high-resolution …
variance, have given way to methods that involve several markers and high-resolution …
[КНИГА][B] Statistical genomics: linkage, map**, and QTL analysis
BH Liu - 2017 - taylorfrancis.com
Statistical Genomics: Linkage, Map**, and QTL Analysis Page 1 Page 2 Statistical Genomics
Linkage, Map**, and QTL Analysis CRCPress Ben Hui Liu Boca Raton London New York …
Linkage, Map**, and QTL Analysis CRCPress Ben Hui Liu Boca Raton London New York …
Permutation tests for multiple loci affecting a quantitative character
The problem of detecting minor quantitative trait loci (QTL) responsible for genetic variation
not explained by major QTL is of importance in the complete dissection of quantitative …
not explained by major QTL is of importance in the complete dissection of quantitative …
A simple method to calculate resolving power and confidence interval of QTL map location
A Darvasi, M Soller - Behavior genetics, 1997 - Springer
Abstract “Resolving power” is defined as the 95% confidence interval for quantitative trait
locus (QTL) map location that would be obtained when scoring an infinite number of markers …
locus (QTL) map location that would be obtained when scoring an infinite number of markers …
DNA markers and plant breeding programs
M Lee - Advances in agronomy, 1995 - Elsevier
Publisher Summary On a worldwide basis, plant breeding has been one of the most
successful technologies developed in modern agriculture: its methods are opportunistic and …
successful technologies developed in modern agriculture: its methods are opportunistic and …
A simple correction for multiple comparisons in interval map** genome scans
JM Cheverud - Heredity, 2001 - nature.com
Several approaches have been proposed to correct point-wise significance thresholds used
in interval-map** genome scans. A method for significance threshold correction based on …
in interval-map** genome scans. A method for significance threshold correction based on …
Confidence intervals in QTL map** by bootstrap**
The determination of empirical confidence intervals for the location of quantitative trait loci
(QTLs) was investigated using simulation. Empirical confidence intervals were calculated …
(QTLs) was investigated using simulation. Empirical confidence intervals were calculated …
Statistical methods for map** quantitative trait loci from a dense set of markers
J Dupuis, D Siegmund - Genetics, 1999 - academic.oup.com
Lander and Botstein introduced statistical methods for searching an entire genome for
quantitative trait loci (QTL) in experimental organisms, with emphasis on a backcross design …
quantitative trait loci (QTL) in experimental organisms, with emphasis on a backcross design …
LOD significance thresholds for QTL analysis in experimental populations of diploid species
JW Van Ooijen - Heredity, 1999 - nature.com
Linkage analysis with molecular genetic markers is a very powerful tool in the biological
research of quantitative traits. The lack of an easy way to know what areas of the genome …
research of quantitative traits. The lack of an easy way to know what areas of the genome …