The impact of translocations and gene fusions on cancer causation
Chromosome aberrations, in particular translocations and their corresponding gene fusions,
have an important role in the initial steps of tumorigenesis; at present, 358 gene fusions …
have an important role in the initial steps of tumorigenesis; at present, 358 gene fusions …
DNA hypomethylation in cancer cells
M Ehrlich - Epigenomics, 2009 - Taylor & Francis
DNA hypomethylation was the initial epigenetic abnormality recognized in human tumors.
However, for several decades after its independent discovery by two laboratories in 1983, it …
However, for several decades after its independent discovery by two laboratories in 1983, it …
ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas
KC Wiegand, SP Shah, OM Al-Agha… - … England Journal of …, 2010 - Mass Medical Soc
Background Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis,
but the molecular events involved in this transformation have not been described. Methods …
but the molecular events involved in this transformation have not been described. Methods …
Database resources of the national center for biotechnology information
In addition to maintaining the GenBank® nucleic acid sequence database, the National
Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for …
Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for …
[BOOK][B] Mendelian inheritance in man: a catalog of human genes and genetic disorders
VA McKusick - 1998 - books.google.com
The twelfth edition of this classic reference work includes:-More than 2,000 new entries-A
total of more than 9,000 entries-New features and enhancement of the familiar old features …
total of more than 9,000 entries-New features and enhancement of the familiar old features …
Database resources of the national center for biotechnology information
DL Wheeler, T Barrett, DA Benson… - Nucleic acids …, 2007 - academic.oup.com
In addition to maintaining the GenBank (R) nucleic acid sequence database, the National
Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for …
Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for …
[HTML][HTML] A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
JR Bischoff, L Anderson, Y Zhu, K Mossie, L Ng… - The EMBO …, 1998 - embopress.org
Genetic and biochemical studies in lower eukaryotes have identified several proteins that
ensure accurate segregation of chromosomes. These include the Drosophila aurora and …
ensure accurate segregation of chromosomes. These include the Drosophila aurora and …
Guanine nucleotide exchange factors for Rho GTPases: turning on the switch
A Schmidt, A Hall - Genes & development, 2002 - genesdev.cshlp.org
Rho GTPases control many aspects of cell behavior through the regulation of multiple signal
transduction pathways (Van Aelst and D'Souza-Schorey 1997; Hall 1998). Rho, Rac, and …
transduction pathways (Van Aelst and D'Souza-Schorey 1997; Hall 1998). Rho, Rac, and …
Activation of homologous recombination in G1 preserves centromeric integrity
Centromeric integrity is key for proper chromosome segregation during cell division.
Centromeres have unique chromatin features that are essential for centromere …
Centromeres have unique chromatin features that are essential for centromere …
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene KILLER/DR5 is a
DNA damage-inducible p53-regulated death receptor gene Nat Genet. 1997 Oct;17(2):141-3 …
DNA damage-inducible p53-regulated death receptor gene Nat Genet. 1997 Oct;17(2):141-3 …