Sex differences in anxiety and depression: circuits and mechanisms

DA Bangasser, A Cuarenta - Nature Reviews Neuroscience, 2021 - nature.com
Epidemiological sex differences in anxiety disorders and major depression are well
characterized. Yet the circuits and mechanisms that contribute to these differences are …

Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

[HTML][HTML] Social brain, social dysfunction and social withdrawal

S Porcelli, N Van Der Wee, S van der Werff… - Neuroscience & …, 2019 - Elsevier
The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

[HTML][HTML] Roles of oxytocin in stress responses, allostasis and resilience

Y Takayanagi, T Onaka - International journal of molecular sciences, 2021 - mdpi.com
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …

Fighting females: neural and behavioral consequences of social defeat stress in female mice

EL Newman, HE Covington III, J Suh, MB Bicakci… - Biological …, 2019 - Elsevier
Background Despite the twofold higher prevalence of major depressive and posttraumatic
stress disorders in women compared with men, most clinical and preclinical studies have …

Neurobiology of loneliness, isolation, and loss: integrating human and animal perspectives

EM Vitale, AS Smith - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
In social species such as humans, non-human primates, and even many rodent species,
social interaction and the maintenance of social bonds are necessary for mental and …

Extrahypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance

N Duque-Wilckens, LY Torres, S Yokoyama… - Proceedings of the …, 2020 - pnas.org
Oxytocin increases the salience of both positive and negative social contexts and it is
thought that these diverse actions on behavior are mediated in part through circuit-specific …

Oxytocin alleviates cognitive and memory impairments by decreasing hippocampal microglial activation and synaptic defects via OXTR/ERK/STAT3 pathway in a …

J Jiang, Y Zou, C ** techniques are becoming more prevalent in the field of
behavioral neuroscience, and thus methods for manipulating neuronal activity must be …