Abstract Industry 4.0, the new wave of Smart Manufacturing in Europe and globally, relies on
a Digital Thread to connect the data and processes for smarter products, smarter production …

We review our experience with integrating Artificial Intelligence (AI) into healthcare systems
following the Model-Driven Development (MDD) approach. At a time when AI has the …

An up-to-date personal health record (PHR) system is crucial for people's health. Achieving
a reliable PHR system in the e-Health and m-Health era is still a challenge concerning data …

This paper reviews the development of Model-Driven Software Engineering (MDSE) from its
origins to the present day. The paper discusses the components of models, modelling …

We present DIME, an integrated solution for the rigorous model-driven development of
sophisticated web applications based on the Dynamic Web Application (DyWA) framework …

With the heterogeneity of the industry 4.0 world, and more generally of the Cyberphysical
Systems realm, the quest towards a platform approach to solve the interoperability problem …

In this paper, we present the paradigm of Language-Driven Engineering (LDE), which is
characterized by its unique support for division of labour on the basis of Domain-Specific …

CMDE has been successfully applied in several industrial projects, including
telecommunication services, supply-chain management, bioinformatics, logistics, and …

We present Pyrus, a domain-specific online modeling environment for building graphical
processes for data analysis, machine learning and artificial intelligence. Pyrus aims at …

This book addresses the challenge of user-level workflow design with a particular focus on
the bioinformatics application domain. Towards this aim, it follows a novel, constraint-driven …