When force met fluorescence: single-molecule manipulation and visualization of protein–DNA interactions

GNL Chua, S Liu - Annual Review of Biophysics, 2024 - annualreviews.org
Myriad DNA-binding proteins undergo dynamic assembly, translocation, and conformational
changes while on DNA or alter the physical configuration of the DNA substrate to control its …

The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA

SR Hengel, KG Oppenheimer, CM Smith… - Nature …, 2024 - nature.com
Templated DNA repair that occurs during homologous recombination and replication stress
relies on RAD51. RAD51 activity is positively regulated by BRCA2 and the RAD51 paralogs …

Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models

EA Pedersen, ME Verhaegen, MK Joseph… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma
thought to arise via either viral (Merkel cell polyomavirus) or ultraviolet-associated pathways …

Le complexe de réplication des poxvirus: cible potentielle de molécules antivirales

N Tarbouriech, WP Burmeister, B Bersch, F Iseni - Virologie, 2024 - stm.cairn.info
1 La famille des Poxviridae, qui regroupe des virus à ADN double brin linéaire, se divise en
deux sous-familles selon leur spécificité d'hôte: les virus appartenant à la sous-famille des …

Poxvirus-encoded DNA replication proteins: potential targets for antivirals

N Tarbouriech, WP Burmeister, B Bersch, F Iseni - Virologie, 2024 - jle.com
JLE - Virologie - Poxvirus-encoded DNA replication proteins: potential targets for antivirals
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