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A causal role for hyperinsulinemia in obesity
Insulin modulates the biochemical pathways controlling lipid uptake, lipolysis and
lipogenesis at multiple levels. Elevated insulin levels are associated with obesity, and …
lipogenesis at multiple levels. Elevated insulin levels are associated with obesity, and …
Mild suppression of hyperinsulinemia to treat obesity and insulin resistance
Insulin plays roles in lipid uptake, lipolysis, and lipogenesis, in addition to controlling blood
glucose levels. Excessive circulating insulin is associated with adipose tissue expansion …
glucose levels. Excessive circulating insulin is associated with adipose tissue expansion …
Combination of high-fat/high-fructose diet and low-dose streptozotocin to model long-term type-2 diabetes complications
DA Barrière, C Noll, G Roussy, F Lizotte, A Kessai… - Scientific Reports, 2018 - nature.com
The epidemic of type 2 diabetes mellitus (T2DM) is fueled by added fructose consumption.
Here, we thus combined high-fat/high-fructose diet, with multiple low-dose injections of …
Here, we thus combined high-fat/high-fructose diet, with multiple low-dose injections of …
The gut microbiome and type 2 diabetes status in the Multiethnic Cohort
Background The gut microbiome may play a role in inflammation associated with type 2
diabetes (T2D) development. This cross-sectional study examined its relation with glycemic …
diabetes (T2D) development. This cross-sectional study examined its relation with glycemic …
Diabetes pharmacotherapy and effects on the musculoskeletal system
Persons with type 1 or type 2 diabetes have a significantly higher fracture risk than age‐
matched persons without diabetes, attributed to disease‐specific deficits in the …
matched persons without diabetes, attributed to disease‐specific deficits in the …
[HTML][HTML] From an apple to a pear: moving fat around for reversing insulin resistance
Type 2 diabetes (T2D) is a chronic condition where the body is resistant to insulin, leading to
an elevated blood glucose state. Obesity is a main factor leading to T2D. Many clinical …
an elevated blood glucose state. Obesity is a main factor leading to T2D. Many clinical …
In-situ formable dextran/chitosan-based hydrogels functionalized with collagen and EGF for diabetic wounds healing
P Hu, Q Lei, S Duan, Y Fu, H Pan, C Chang… - Biomaterials …, 2022 - Elsevier
Delayed or non-healing skin wounds causing gangrene or even amputation, greatly threats
diabetic patients lives. Herein, a bioactive, in-situ formable hydrogel based wound dressing …
diabetic patients lives. Herein, a bioactive, in-situ formable hydrogel based wound dressing …
[HTML][HTML] Vitamin D mitigates diabetes-associated metabolic and cognitive dysfunction by modulating gut microbiota and colonic cannabinoid receptor 1
Introduction Obesity is associated with elevated endocannabinoid tone, gut dysbiosis, and
inflammation predisposing to diabetes. The endocannabinoid system mediates the effects of …
inflammation predisposing to diabetes. The endocannabinoid system mediates the effects of …
Effect of Lactobacillus fermentum TKSN041 on improving streptozotocin-induced type 2 diabetes in rats
X Zhou, G Shang, Q Tan, Q He, X Tan, KY Park… - Food & Function, 2021 - pubs.rsc.org
With the increasing incidence of type 2 diabetes, it is imperative to identify how to effectively
prevent or treat this disease. Studies have shown that some lactic acid bacteria can improve …
prevent or treat this disease. Studies have shown that some lactic acid bacteria can improve …
[PDF][PDF] Effects of ginsenoside Rg1 on glucose metabolism and liver injury in streptozotocin-induced type 2 diabetic rats
W Tian, L Chen, L Zhang, B Wang, XB Li… - Genet Mol …, 2017 - m.jstshuichan.com
Type 2 diabetes mellitus (T2-DM) is a chronic metabolic disorder characterized by high
blood glucose levels. T2-DM patients suffer from many complications, such as diabetic fatty …
blood glucose levels. T2-DM patients suffer from many complications, such as diabetic fatty …