SARS-CoV-2 Omicron variants: burden of disease, impact on vaccine effectiveness and need for variant-adapted vaccines

S Pather, SA Madhi, BJ Cowling, P Moss… - Frontiers in …, 2023 - frontiersin.org
The highly transmissible Omicron (B. 1.1. 529) variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) was first detected in late 2021. Initial Omicron waves were …

Omicron variant evolution on vaccines and monoclonal antibodies

M Sabbatucci, A Vitiello, S Clemente, A Zovi… - …, 2023 - Springer
The severe acute respiratory syndrome coronavirus (SARS-CoV)-2 responsible for the
global COVID-19 pandemic has caused almost 760 million confirmed cases and 7 million …

Hospital outcomes of community-acquired SARS-CoV-2 Omicron variant infection compared with influenza infection in Switzerland

L Portmann, MEA de Kraker, G Fröhlich… - JAMA Network …, 2023 - jamanetwork.com
Importance With the ongoing COVID-19 pandemic, it is crucial to assess the current burden
of disease of community-acquired SARS-CoV-2 Omicron variant in hospitalized patients to …

Effectiveness of BNT162b2 and CoronaVac in children and adolescents against SARS-CoV-2 infection during Omicron BA. 2 wave in Hong Kong

D Leung, JS Rosa Duque, KM Yip, HK So… - Communications …, 2023 - nature.com
Abstract Background The SARS-CoV-2 Omicron BA. 2 subvariant replaced BA. 1 globally in
early 2022, and caused an unprecedented tsunami of cases in Hong Kong, resulting in the …

[HTML][HTML] Distinct clinical and laboratory features of COVID-19 in children during the pre-delta, delta and omicron wave

MS Han, KM Kim, KJ Oh, JY Chang… - The Pediatric …, 2023 - journals.lww.com
Background: The SARS-CoV-2 variants of concern exhibit distinct features in terms of
transmissibility and virulence. This study compared the clinical characteristics of COVID-19 …

Effectiveness of monovalent mRNA vaccines against omicron XBB infection in Singaporean children younger than 5 years

LE Wee, N Tang, D Pang, C Chiew, CF Yung… - JAMA …, 2023 - jamanetwork.com
Importance Literature on vaccine effectiveness of SARS-CoV-2 messenger RNA (mRNA)
vaccines for children younger than 5 years is limited. Objective To report the effectiveness of …

Clinical presentation and severity of SARS-CoV-2 infection compared to respiratory syncytial virus and other viral respiratory infections in children less than two years …

F Nunziata, S Salomone, A Catzola, M Poeta… - Viruses, 2023 - mdpi.com
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the
implementation of restrictive measures led to a dramatic reduction in respiratory syncytial …

Intranasal infection by SARS-CoV-2 Omicron variants can induce inflammatory brain damage in newly weaned hamsters

C Li, W Song, JFW Chan, Y Chen, F Liu… - Emerging Microbes & …, 2023 - Taylor & Francis
Children infected by SARS-CoV-2 Omicron variant may develop neurological complications.
To study the pathogenesis in the growing brain, we intranasally challenged newly-weaned …

COVID-19 vaccines versus pediatric hospitalization

JSR Duque, D Leung, KM Yip, DHL Lee, H So… - Cell Reports …, 2023 - cell.com
Vaccine effectiveness of BNT162b2 and CoronaVac against COVID-19-associated
hospitalization and moderate-to-severe disease due to SARS-CoV-2 Omicron BA. 2 is …

[HTML][HTML] Critical pediatric neurological illness associated with COVID-19 (Omicron BA. 2.3. 7 variant) infection in Taiwan: immunological assessment and viral genome …

CS Chen, CN Chang, CF Hu, MJ Jian… - International Journal of …, 2022 - Elsevier
Abstract Objectives Since April 2022, another wave of the Omicron epidemic has struck
Taiwanese society, and children with severe neurological complications have been reported …