Natural and synthetic polymeric hydrogel: a bioink for 3D bioprinting of tissue models

P Brahme, N Rarokar, R Kumbhalkar, S Saoji… - Journal of Drug Delivery …, 2024 - Elsevier
Bioprinting is an emerging field that is revolutionizing medicine, it offers great cells, proteins,
improving genes, drugs, and bioactive particle controls, tissue generation and formation …

An approach for an enhanced anticancer activity of ferulic acid-loaded polymeric micelles via MicroRNA-221 mediated activation of TP53INP1 in caco-2 cell line

NM Sweed, MHS Dawoud, NM Aborehab, SM Ezzat - Scientific Reports, 2024 - nature.com
Ferulic acid (FA) has powerful antioxidant and antitumor activities, but it has low
bioavailability owing to its poor water solubility. Our aim is to formulate polymeric mixed …

Functionalized folate-modified graphene oxide/PEI siRNA nanocomplexes for targeted ovarian cancer gene therapy

Y Wang, G Sun, Y Gong, Y Zhang, X Liang… - Nanoscale research …, 2020 - Springer
Gene therapy is emerging as a valid method for the treatment of ovarian cancer, including
small interfering RNA (siRNA). Although it is so powerful, few targeting efficient gene …

Preparation of Terbinafin-Encapsulated Solid Lipid Nanoparticles Containing Antifungal Carbopol® Hydrogel with Improved Efficacy: In Vitro, Ex Vivo and In Vivo …

NR Rarokar, SS Menghani, DR Kerzare, PB Khedekar… - Pharmaceutics, 2022 - mdpi.com
The present research was aimed to develop a terbinafin hydrochloride (TH)-encapsulated
solid lipid nanoparticles (SLNs) hydrogel for improved antifungal efficacy. TH-loaded SLNs …

An injectable carboxymethyl chitosan-methylcellulose-pluronic hydrogel for the encapsulation of meloxicam loaded nanoparticles

S Fattahpour, M Shamanian, N Tavakoli, M Fathi… - International journal of …, 2020 - Elsevier
Hydrogel scaffolds have been frequently utilized due to their ability to absorb water and
develop similar body cell conditions. Specific drug delivery to the tissues ensures less …

Phospholipid based colloidal nanocarriers for enhanced solubility and therapeutic efficacy of withanolides

SD Saoji, NR Rarokar, PW Dhore, SO Dube… - Journal of Drug Delivery …, 2022 - Elsevier
The bioactive withanolides of Withania somnifera (WS) are reported to treat acute stress-
induced anxiety and chronic stress-induced depression. However, its biopharmaceutical …

Design and optimization of chitosan-coated solid lipid nanoparticles containing insulin for improved intestinal permeability using piperine

I Raghunath, M Koland, C Sarathchandran… - International Journal of …, 2024 - Elsevier
The objective of this research was to optimize the composition and performance of chitosan-
coated solid lipid nanoparticles carrying insulin (Ch-In-SLNs) and to assess the potential of …

[HTML][HTML] Thermogels based on biocompatible OEGMA-MEGMA diblock copolymers

Q Li, R Wang, J Lee, JS Correia… - European Polymer …, 2023 - Elsevier
A series of biocompatible thermoresponsive copolymers were successfully synthesised via
group transfer polymerisation (GTP) from methoxy ethylene glycol methacrylate (MEGMA) …

Meloxicam encapsulated nanostructured colloidal self‐assembly for evaluating antitumor and anti‐inflammatory efficacy in 3D printed scaffolds

N Rarokar, S Gurav, P Khedekar - Journal of Biomedical …, 2021 - Wiley Online Library
Nanostructured colloidal self‐assembly (NCS) is one of the most promising drug delivery
carriers in cancer treatment. The present research work aimed towards synthesizing …

One-step synthesis of nitrogen-doped hydrophilic mesoporous carbons from chitosan-based triconstituent system for drug release

X Wang, H Pan, Q Lin, H Wu, S Jia, Y Shi - Nanoscale research letters, 2019 - Springer
In situ nitrogen-doped hydrophilic mesoporous carbon spheres with different carbon-to-
silicon (C/Si) ratios (NMCs-x/3, x= 5, 6, 7, and 8) were prepared by one-step method coupled …