Nanodiscs in membrane biochemistry and biophysics

IG Denisov, SG Sligar - Chemical reviews, 2017 - ACS Publications
Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Self-assembly concepts for multicompartment nanostructures

AH Gröschel, AHE Müller - Nanoscale, 2015 - pubs.rsc.org
Compartmentalization is ubiquitous to many biological and artificial systems, be it for the
separate storage of incompatible matter or to isolate transport processes. Advancements in …

Biomolecular assemblies: moving from observation to predictive design

CJ Wilson, AS Bommarius, JA Champion… - Chemical …, 2018 - ACS Publications
Biomolecular assembly is a key driving force in nearly all life processes, providing structure,
information storage, and communication within cells and at the whole organism level. These …

Exploring molecular-biomembrane interactions with surface plasmon resonance and dual polarization interferometry technology: expanding the spotlight onto …

TH Lee, DJ Hirst, K Kulkarni, MP Del Borgo… - Chemical …, 2018 - ACS Publications
The molecular analysis of biomolecular-membrane interactions is central to understanding
most cellular systems but has emerged as a complex technical challenge given the …

Mucin-1-antibody-conjugated mesoporous silica nanoparticles for selective breast cancer detection in a mucin-1 transgenic murine mouse model

D Dréau, LJ Moore, MP Alvarez-Berrios… - Journal of …, 2016 - ingentaconnect.com
Mucin-1 (MUC1), a transmembrane glycoprotein is aberrantly expressed on∼ 90% of breast
cancer and is an excellent target for nanoparticulate targeted imaging. In this study, the …

Application of nucleic acid–lipid conjugates for the programmable organisation of liposomal modules

PA Beales, TK Vanderlick - Advances in colloid and interface science, 2014 - Elsevier
We present a critical review of recent work related to the assembly of multicompartment
liposome clusters using nucleic acids as a specific recognition unit to link liposomal …

DNA‐Grafted Supramolecular Polymers: Helical Ribbon Structures Formed by Self‐Assembly of Pyrene–DNA Chimeric Oligomers

Y Vyborna, M Vybornyi, AV Rudnev… - Angewandte Chemie …, 2015 - Wiley Online Library
The controlled arraying of DNA strands on adaptive polymeric platforms remains a
challenge. Here, the noncovalent synthesis of DNA‐grafted supramolecular polymers from …

Cellular endocytosis and trafficking of cholera toxin B-modified mesoporous silica nanoparticles

WA Walker, M Tarannum… - Journal of Materials …, 2016 - pubs.rsc.org
In this study, mesoporous silica nanoparticles (MSNs) were functionalized with cholera toxin
subunit B (CTxB) protein to influence their intracellular trafficking pathways. The CTxB–MSN …

Nanodiscoidal Nucleic Acids for Gene Regulation

R Sharma, S Narum, S Liu, Y Dong, KI Baek… - ACS Chemical …, 2023 - ACS Publications
Therapeutic nucleic acids represent a powerful class of drug molecules to control gene
expression and protein synthesis. A major challenge in this field is that soluble …

Programmable nanodisc patterning by DNA origami

Z Zhang, ER Chapman - Nano letters, 2020 - ACS Publications
Nanodiscs (ND) are soluble phospholipid bilayers bounded by membrane scaffold proteins;
they have become invaluable in the study of membrane proteins. However, this …