After three decades of developments, single particle tracking (SPT) has become a powerful
tool to interrogate dynamics in a range of materials including live cells and novel catalytic …

The tremendous progress in the synthesis of different inorganic nanoparticles with
pretailored size, shape, structural, compositional, and surface properties has significantly …

RNA-protein (RNP) granules have been proposed to assemble by forming solid RNA/protein
aggregates or through phase separation into a liquid RNA/protein phase. Which model …

In response to lysosomal damage, cells engage several quality-control mechanisms,
including the selective isolation and degradation of damaged lysosomes by lysophagy …

How cells adapt to varying environmental conditions is largely unknown. Here, we show
that, in budding yeast, the RNA-binding and stress granule protein Pub1 has an intrinsic …

Liquid–liquid phase separation (LLPS) emerges as a fundamental underlying mechanism
for the biological organization, especially the formation of membraneless organelles (MLOs) …

The ability of cells to adhere and sense differences in tissue stiffness is crucial for organ
development and function. The central mechanisms by which adherent cells detect …

Focal adhesions (FAs) are macromolecular complexes that regulate cell adhesion and
mechanotransduction. By performing fluorescence recovery after photobleaching (FRAP) …

The link between extracellular-matrix-bound integrins and intracellular F-actin is essential
for cell spreading and migration. Here, we demonstrate how the actin-binding proteins talin …

The phase separation of biomolecules has become the focus of intense research in the past
decade, with a growing body of research implicating this phenomenon in essentially all …