Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Aging is a dynamic, time-dependent process that is characterized by a gradual accumulation
of cell damage. Continual functional decline in the intrinsic ability of living organisms to …

Senescent cells remain metabolically active, but their metabolic landscape and resulting
implications remain underexplored. Here, we report upregulation of pyruvate …

The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …

Abstract Purpose of Review Skeletal muscle and bone are connected anatomically and
physiologically, and play a crucial role in human locomotion and metabolism. Historically …

Aging impairs tendon stem/progenitor cell function and tendon homeostasis, however,
effective treatments for aging‐induced tendon diseases are lacking. Exosomes are naturally …

Whether and how certain transposable elements with viral origins, such as endogenous
retroviruses (ERVs) dormant in our genomes, can become awakened and contribute to the …

Ageing is an inevitable event in the lifecycle of all organisms, characterized by progressive
physiological deterioration and increased vulnerability to death. Ageing has also been …

Ageing is characterized by the functional decline of tissues and organs and the increased
risk of ageing-associated disorders. Several 'rejuvenating'interventions have been proposed …