Acute respiratory distress syndrome (ARDS) is characterized by severe impairment of gas
exchange. Hypoxemia is mainly due to intrapulmonary shunt, whereas increased alveolar …

Purpose The clinical use of vasoactive drugs is not only intended to improve systemic
hemodynamic variables, but ultimately to attenuate derangements in organ perfusion and …

Integrating basic and clinical research on the biophysical and physiological functions of
pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on …

Objective. A prominent feature of sepsis is dysfunction of the microcirculation, with impaired
perfusion and regional tissue oxygenation causing a deficit in oxygen extraction. If shunting …

Study objectives This study was carried out to determine the efficacy of and dose-response
relationships to inhaled aerosolized prostacyclin (IAP), when used as a selective pulmonary …

OBJECTIVE: The objective of this study was to compare the efficacy of inhaled iloprost and
nitric oxide (iNO) in reducing pulmonary hypertension (PHT) during cardiac surgery …

Background: There are two independent head injury outcome studies using the “Lund
concept”, and both showed a mortality rate of about 10%, and a favourable outcome …

We describe the case of a 28‐week pregnant woman presenting with severe primary
pulmonary hypertension (PPH). She had an elective Caesarean section under general …

Objectives To examine the hypothesis that the response to inhaled prostacyclin (PGI 2) on
oxygenation and pulmonary hemodynamics may be related to different morphologic features …

Interventions Aerosolized prostacyclin (epoprostenol sodium) by stepwise increments of
different doses (10, 20, 30, 40, and 50 ng· kg− 1· min− 1) vs. aerosolized normal saline …