Genetic polymorphisms in sepsis

A Namath, AJ Patterson - Critical Care Nursing Clinics, 2011 - ccnursing.theclinics.com
Host predisposition influences risk of 1 and outcome during sepsis. 1, 2 Genetic
polymorphisms represent interindividual genetic variability and may help to explain host …

Multiplexed prostate cancer companion diagnostic devices

J Aidoo-Brown, D Moschou, P Estrela - Sensors, 2021 - mdpi.com
Prostate cancer (PCa) remains one of the most prominent forms of cancer for men. Since the
early 1990s, Prostate-Specific Antigen (PSA) has been a commonly recognized PCa …

Evaluation of potential biomarkers for the discrimination of bacterial and viral infections

P Chalupa, O Beran, H Herwald, N Kaspříková… - Infection, 2011 - Springer
Purpose Timely knowledge of the bacterial etiology and localization of infection are
important for empirical antibiotic therapy. Thus, the goal of this study was to evaluate …

Automated 3D-printed microfluidic array for rapid nanomaterial-enhanced detection of multiple proteins

K Kadimisetty, S Malla, KS Bhalerao, IM Mosa… - Analytical …, 2018 - ACS Publications
We report here the fabrication and validation of a novel 3D-printed, automated immunoarray
to detect multiple proteins with ultralow detection limits. This low cost, miniature …

Prostate cancer diagnosis in the clinic using an 8-protein biomarker panel

AL Jones, L Dhanapala, TA Baldo… - Analytical …, 2020 - ACS Publications
The inability to distinguish aggressive from indolent prostate cancer is a longstanding
clinical problem. Prostate specific antigen (PSA) tests and digital rectal exams cannot …

Accessible telemedicine diagnostics with ELISA in a 3D printed pipette tip

M Sharafeldin, K Kadimisetty, KR Bhalerao… - Analytical …, 2019 - ACS Publications
We report herein a novel pipet-based “ELISA in a tip” as a new versatile diagnostic tool
featuring better sensitivity, shorter incubation time, accessibility, and low sample and …

Metabolomics in sepsis and its impact on public health

N Evangelatos, P Bauer, M Reumann… - Public Health …, 2018 - karger.com
Sepsis, with its often devastating consequences for patients and their families, remains a
major public health concern that poses an increasing financial burden. Early resuscitation …

Sepsis biomarkers: an omics perspective

X Liu, H Ren, D Peng - Frontiers of medicine, 2014 - Springer
Sepsis is a common cause of death in hospitalized patients worldwide. The early detection
of sepsis remains a great challenge for clinicians, and delayed diagnosis frequently …

Genetic predisposition to respiratory infection and sepsis

LP Chung, GW Waterer - Critical reviews in clinical laboratory …, 2011 - Taylor & Francis
Genetic variations, in part, determine individual susceptibility to sepsis and pneumonia.
Advances in genetic sequence analysis as well as high throughput platform analysis of gene …

From traditional biochemical signals to molecular markers for detection of sepsis after burn injuries

B Muñoz, R Suárez-Sánchez… - Burns, 2019 - Elsevier
Sepsis is a life-threatening organ-dysfunction condition caused by a dysregulated response
to an infectious condition that can cause complications in patients with major trauma. Burns …