In-vivo Raman spectroscopy: from basics to applications

E Cordero, I Latka, C Matthäus… - Journal of biomedical …, 2018‏ - spiedigitallibrary.org
For more than two decades, Raman spectroscopy has found widespread use in biological
and medical applications. The instrumentation and the statistical evaluation procedures …

Current advances in the diagnostic imaging of atherosclerosis: insights into the pathophysiology of vulnerable plaque

NV Mushenkova, VI Summerhill, D Zhang… - International journal of …, 2020‏ - mdpi.com
Atherosclerosis is a lipoprotein-driven inflammatory disorder leading to a plaque formation
at specific sites of the arterial tree. After decades of slow progression, atherosclerotic plaque …

Raman spectroscopy and imaging in bioanalytics

D Cialla-May, C Krafft, P Rösch… - Analytical …, 2021‏ - ACS Publications
Since the discovery of the inelastic scattering of light, ie, the so-called Raman effect, 1
Raman spectroscopy has become an attractive tool in a high number of research fields …

Physicochemical understanding of biomineralization by molecular vibrational spectroscopy: From mechanism to nature

H Liu, H Jiang, X Liu, X Wang - Exploration, 2023‏ - Wiley Online Library
The process and mechanism of biomineralization and relevant physicochemical properties
of mineral crystals are remarkably sophisticated multidisciplinary fields that include biology …

Mesoscopic fluorescence lifetime imaging: Fundamental principles, clinical applications and future directions

A Alfonso‐Garcia, J Bec, B Weyers… - Journal of …, 2021‏ - Wiley Online Library
Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …

SERS as an analytical tool in environmental science: the detection of sulfamethoxazole in the nanomolar range by applying a microfluidic cartridge setup

S Patze, U Huebner, F Liebold, K Weber… - Analytica chimica …, 2017‏ - Elsevier
Sulfamethoxazole (SMX) is a commonly applied antibiotic for treating urinary tract infections;
however, allergic reactions and skin eczema are known side effects that are observed for all …

Looking for a perfect match: multimodal combinations of Raman spectroscopy for biomedical applications

IW Schie, C Stiebing, J Popp - Journal of Biomedical Optics, 2021‏ - spiedigitallibrary.org
Raman spectroscopy has shown very promising results in medical diagnostics by providing
label-free and highly specific molecular information of pathological tissue ex vivo and in …

A machine learning framework to analyze hyperspectral stimulated Raman scattering microscopy images of expressed human meibum

A Alfonso‐García, J Paugh, M Farid… - Journal of Raman …, 2017‏ - Wiley Online Library
We develop and discuss a methodology for batch‐level analysis of hyperspectral stimulated
Raman scattering (hsSRS) data sets of human meibum in the CH‐stretching vibrational …

Dual-modality optical coherence tomography and frequency-domain fluorescence lifetime imaging microscope system for intravascular imaging

X Chen, W Kim, MJ Serafino, Z Tan… - Journal of …, 2020‏ - spiedigitallibrary.org
Significance: Detailed biochemical and morphological imaging of the plaque burdened
coronary arteries holds the promise of improved understanding of atherosclerosis plaque …

[HTML][HTML] Scanning acoustic microscopy and time-resolved fluorescence spectroscopy for characterization of atherosclerotic plaques

B Bilen, B Gokbulut, U Kafa, E Heves, MN Inci… - Scientific Reports, 2018‏ - nature.com
Atherosclerotic plaques constitute the primary cause of heart attack and stroke. However, we
still lack a clear identification of the plaques. Here, we evaluate the feasibility of scanning …