The number of druggable tumor-specific molecular aberrations has grown substantially in
the past decade, with a significant survival benefit obtained from biomarker matching …

In the late 19th century, formalin fixation with paraffin-embedding (FFPE) of tissues was
developed as a fixation and conservation method and is still used to this day in routine …

Genoty**‐in‐Thousands by sequencing (GT‐seq) is a method that uses next‐generation
sequencing of multiplexed PCR products to generate genotypes from relatively small panels …

Next-generation sequencing (NGS) has been rapidly integrated into molecular pathology,
dramatically increasing the breadth genomic of information available to oncologists and their …

Formalin-fixed paraffin-embedded (FFPE) tissue blocks are widely used to identify clinically
actionable molecular alterations or perform retrospective molecular studies. Our goal was to …

Next-generation sequencing (NGS) genomic oncology profiling assays have emerged as
key drivers of personalized cancer care and translational research. However, validation of …

Background Targeted Next Generation Sequencing (NGS) offers a way to implement testing
of multiple genetic aberrations in diagnostic pathology practice, which is necessary for …

Owing to the high throughput and low cost, next generation sequencing has attracted much
attention for SNP genoty** application for researchers. Here, we introduce a new method …

Background: Data on non-small-cell lung cancer (NSCLC) patients with non-classic
epidermal growth factor receptor (EGFR) mutations are scarce, especially in non-Asian …

In this study, we evaluate the expression of human papillomavirus E4 protein (marker for the
onset of a productive infection) and hypermethylation of host-cell CADM1, MAL, and miR124 …