Patient-specific cardiac models are now being used to guide therapies. The increased use
of patient-specific cardiac simulations in clinical care will give rise to the development of …

Mathematical and computational modeling of the cardiovascular system is increasingly
providing non‐invasive alternatives to traditional invasive clinical procedures. Moreover, it …

In this paper, we present an open-source multi-resolution and multi-physics library,
SPHinXsys, which is released under the Apache License (2.0). Along with the source code …

This is a book on Optimal Control Problems (OCPs): how to formulate them, how to set up a
suitable mathematical framework for their analysis, how to approximate them numerically …

Atrial fibrillation (AF) carries out a 5-fold increase in stroke risk, related to embolization of
thrombi clotting in left atrium (LA). Left atrial appendage (LAA) is the site with the highest …

Predicting the electrical behavior of the heart, from the cellular scale to the tissue level, relies
on the numerical approximation of coupled nonlinear dynamical systems. These systems …

In order to simulate the cardiac function for a patient‐specific geometry, the generation of the
computational mesh is crucially important. In practice, the input is typically a set of …

Optimization and uncertainty quantification have been playing an increasingly important role
in computational hemodynamics. However, existing methods based on principled modeling …

Cardiovascular (CV) disease impacts tens of millions of people annually and carries a
massive global economic burden. Continued advances in medical imaging, hardware and …

Aortic dissection continues to be responsible for significant morbidity and mortality, although
recent advances in medical data assimilation and in experimental and in silico models have …