Cardiovascular (CV) disease impacts tens of millions of people annually and carries a
massive global economic burden. Continued advances in medical imaging, hardware and …

Aortic dissection continues to be responsible for significant morbidity and mortality, although
recent advances in medical data assimilation and in experimental and in silico models have …

In this paper, we present an open-source multi-resolution and multi-physics library,
SPHinXsys, which is released under the Apache License (2.0). Along with the source code …

Stenosis is a tiny plaque-like structure that builds up in the arterial wall owing to the
sediment of cholesterol, fats, and pearly substances. Such inward proliferation in arteries …

In order to simulate the cardiac function for a patient‐specific geometry, the generation of the
computational mesh is crucially important. In practice, the input is typically a set of …

Atrial fibrillation (AF) carries out a 5-fold increase in stroke risk, related to embolization of
thrombi clotting in left atrium (LA). Left atrial appendage (LAA) is the site with the highest …

The numerical simulation of multiple scenarios easily becomes computationally prohibitive
for cardiac electrophysiology (EP) problems if relying on usual high-fidelity, full order models …

This is a book on Optimal Control Problems (OCPs): how to formulate them, how to set up a
suitable mathematical framework for their analysis, how to approximate them numerically …

We analyse the haemodynamics of the left atrium, highlighting differences between healthy
individuals and patients affected by atrial fibrillation. The computational study is based on …

Predicting the electrical behavior of the heart, from the cellular scale to the tissue level, relies
on the numerical approximation of coupled nonlinear dynamical systems. These systems …