Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Blood–brain barrier (BBB) strictly controls matter exchange between blood and brain, and
severely limits brain penetration of systemically administered drugs, resulting in ineffective …

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, and it is
associated with poor prognosis. Its characteristics of being highly invasive and undergoing …

The blood–brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …

Central nervous system (CNS) disorders, including brain tumor, ischemic stroke, Alzheimer's
disease, and Parkinson's disease, threaten human health. And the existence of the blood …

As the most dangerous tumors, brain tumors are usually treated with surgical removal,
radiation therapy, and chemotherapy. However, due to the aggressive growth of gliomas …

With the increase of population aging, the number of Alzheimer's disease (AD) patients is
also increasing. According to current estimates, approximately 11% of people over 65 suffer …

Cerebral ischemia/reperfusion (CI/R) injury is a clinical conundrum during the treatment of
ischemic stroke. Cell-derived exosomes (CDE) were proved to be therapeutically effective …

Biomimetic delivery systems (BDSs), inspired by the intricate designs of biological systems,
have emerged as a groundbreaking paradigm in nanomedicine, offering unparalleled …

Exosomes are cell-derived vesicles with a lipid bilayer membrane that play important roles
in intercellular communication. They provide an unprecedented opportunity for the …