Plastics are indispensable in everyday life and industry, but the environmental impact of
plastic waste on ecosystems and human health is a huge concern. Microbial biotechnology …

Metabolic burden is defined by the influence of genetic manipulation and environmental
perturbations on the distribution of cellular resources. The rewiring of microbial metabolism …

Highlights●Why biofuels and bioproducts remain critical to society●What molecular
products can be made by biotechnology using available feedstocks●How new systems and …

The adverse effects of waste generation on the environment and public health have raised
global concerns. The utilization of waste as a raw material to develop products with …

Highlights•Efficient microbial cell factories are developed by systems metabolic
engineering.•Recent advances in systems metabolic engineering tools and strategies are …

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Polyamides, also known as nylons, are important industrial polymers with repeating amide
bonds. With the growing concern about climate change, technologies that can establish the …

Microbial cell factories (MCFs) have been leveraged to construct sustainable platforms for
value-added compound production. To optimize metabolism and reach optimal productivity …

Advances in genome engineering and associated technologies have reinvigorated natural
products research. Here we highlight the latest developments in the field across the discover …

Abstract Development of efficient microbial strains for biomanufacturing requires deep
understanding of the biology and functional components responsible for the synthesis …