Haemodialysis (HD) is the commonest form of kidney replacement therapy in the world,
accounting for approximately 69% of all kidney replacement therapy and 89% of all dialysis …

The development of dialysis by early pioneers such as Willem Kolff and Belding Scribner set
in motion several dramatic changes in the epidemiology, economics and ethical frameworks …

Background Several studies have suggested that patients with kidney failure may benefit
from high-dose hemodiafiltration as compared with standard hemodialysis. However, given …

Abstract The National Kidney Foundation's Kidney Disease Outcomes Quality Initiative
(KDOQI) has provided evidence-based guidelines for all stages of chronic kidney disease …

In this narrative review, the biological/biochemical impact (toxicity) of a large array of known
individual uremic retention solutes and groups of solutes is summarized. We classified these …

Haemodialysis is an extracorporeal process in which the blood is cleansed via removal of
uraemic retention products by a semipermeable membrane. Traditionally, dialysis …

Intradialytic hypotension (IDH) is a frequent and serious complication of chronic
haemodialysis, linked to adverse long-term outcomes including increased cardiovascular …

A growing number of publications supports a biologic effect of the protein-bound uremic
retention solutes indoxyl sulfate and p-cresyl sulfate. However, the use of unrealistically high …

There is currently an unmet need for better biomarkers across the spectrum of renal
diseases. In this paper, we revisit the role of beta-2 microglobulin (β2M) as a biomarker in …

This guideline is written primarily for doctors and nurses working in dialysis units and related
areas of medicine in the UK, and is an update of a previous version written in 2009. It aims to …