Is Toxoplasma gondii playing a positive role in multiple sclerosis risk? A systematic review and meta-analysis

R Saberi, M Sharif, S Sarvi, SA Aghayan… - Journal of …, 2018 - Elsevier
Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii with a globally
widespread distribution. The aim of this systematic review and meta-analysis was to …

Is the hygiene hypothesis relevant for the risk of multiple sclerosis?

M Wendel‐Haga, EG Celius - Acta Neurologica Scandinavica, 2017 - Wiley Online Library
The hygiene hypothesis, suggesting that low exposure to pathogens early in life can
increase the risk for immune‐mediated diseases, has been proposed as an explanation for …

Toxoplasma gondii and multiple sclerosis: a population-based case–control study

A Nicoletti, CE Cicero, L Giuliano, V Todaro… - Scientific Reports, 2020 - nature.com
According to the hygiene hypothesis, parasites could have a protective role in the
development of Multiple Sclerosis (MS). Our aim was to assess the association between …

Toxoplasma gondii and multiple sclerosis: A systematic review and meta‐analysis

CE Cicero, FE Allibrio, L Giuliano… - European Journal of …, 2021 - Wiley Online Library
Background and purpose According to the hygiene hypothesis, infections by agents such as
parasites have a protective role against the risk of develo** multiple sclerosis (MS) …

Toxoplasma gondii seropositivity is negatively associated with multiple sclerosis

F Stascheit, F Paul, L Harms, B Rosche - Journal of neuroimmunology, 2015 - Elsevier
Background Toxoplasma (T.) gondii is a ubiquitous intracellular parasitic protozoan that was
recently associated with various autoimmune diseases. Objectives We aimed to investigate …
A Rostami, SM Riahi, A Mollalo… - Transactions of The …, 2022 - academic.oup.com
Previous epidemiologic evidence suggests a protective effect of Toxoplasma gondii infection
against multiple sclerosis (MS) development; however, inconsistent findings have been …

Toxoplasma gondii infection and neuropsychiatric disease: current insight

D Hinze-Selch - Reports in Parasitology, 2015 - Taylor & Francis
Toxoplasma gondii has always been associated with severe medical disease when
acquired congenitally or under immunocompromised conditions. However, in the last …