The n→π* Interaction
Conspectus The carbonyl group holds a prominent position in chemistry and biology not
only because it allows diverse transformations but also because it supports key …
only because it allows diverse transformations but also because it supports key …
C–H⋯ S hydrogen bonding interactions
The short C–H⋯ S contacts found in available structural data for both small molecules and
larger biomolecular systems suggest that such contacts are an often overlooked yet …
larger biomolecular systems suggest that such contacts are an often overlooked yet …
Peptoid nanosheets exhibit a new secondary-structure motif
A promising route to the synthesis of protein-mimetic materials that are capable of complex
functions, such as molecular recognition and catalysis, is provided by sequence-defined …
functions, such as molecular recognition and catalysis, is provided by sequence-defined …
Combining mass spectrometric metabolic profiling with genomic analysis: a powerful approach for discovering natural products from cyanobacteria
An innovative approach was developed for the discovery of new natural products by
combining mass spectrometric metabolic profiling with genomic analysis and resulted in the …
combining mass spectrometric metabolic profiling with genomic analysis and resulted in the …
Small molecular antibacterial peptoid mimics: the simpler the better!
The emergence of multidrug resistant bacteria compounded by the depleting arsenal of
antibiotics has accelerated efforts toward development of antibiotics with novel mechanisms …
antibiotics has accelerated efforts toward development of antibiotics with novel mechanisms …
Palladium‐Catalyzed Enantioselective C− H Olefination to Access Planar‐Chiral Cyclophanes by Dynamic Kinetic Resolution
Z Dong, J Li, T Yao, C Zhao - … Chemie International Edition, 2023 - Wiley Online Library
Planar‐chiral cyclophanes have received increasing attention for drug discovery and
catalyst design. However, the catalytically asymmetric synthesis of planar‐chiral …
catalyst design. However, the catalytically asymmetric synthesis of planar‐chiral …
NDTP mediated direct rapid amide and peptide synthesis without epimerization
Y Li, J Li, G Bao, C Yu, Y Liu, Z He, P Wang, W Ma… - Organic …, 2022 - ACS Publications
Herein, we explored an unprecedented mild, nonirritating, conveniently available, and
recyclable coupling reagent NDTP, which could activate the carboxylic acids via acyl …
recyclable coupling reagent NDTP, which could activate the carboxylic acids via acyl …
Time and Atom Economical Regio‐and Chemoselective Radical Cyclization of Unactivated 1, 6‐Enynes Under Metal‐and Oxidant‐Free Conditions
MR Mutra, J Li, YT Chen… - Chemistry–A European …, 2022 - Wiley Online Library
We developed time‐atom economic regio‐and chemoselective sulfonyl radical triggered 5‐
exo‐dig cyclization of unactivated 1, 6‐enynes with sulfonyl halides under metal, additive …
exo‐dig cyclization of unactivated 1, 6‐enynes with sulfonyl halides under metal, additive …
Cooperative Intramolecular Hydrogen Bonding Strongly Enforces cis-Peptoid Folding
Sequence-defined peptoids, or N-substituted glycines, are an attractive class of bioispired
polymer due to their biostability and efficient synthesis. However, the de novo design of …
polymer due to their biostability and efficient synthesis. However, the de novo design of …
Three-component reaction between alkynes, elemental sulfur, and aliphatic amines: a general, straightforward, and atom economical approach to thioamides
TB Nguyen, MQ Tran, L Ermolenko… - Organic letters, 2014 - ACS Publications
Three-Component Reaction between Alkynes, Elemental Sulfur, and Aliphatic Amines: A
General, Straightforward, and Atom Economical Approach to Thioamides | Organic Letters …
General, Straightforward, and Atom Economical Approach to Thioamides | Organic Letters …