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State-of-the-art strategies for targeting the DNA damage response in cancer
Genomic instability is a key hallmark of cancer that arises owing to defects in the DNA
damage response (DDR) and/or increased replication stress. These alterations promote the …
damage response (DDR) and/or increased replication stress. These alterations promote the …
Autophagy as a molecular target for cancer treatment
Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention
Cancers are caused by mutations that may be inherited, induced by environmental factors,
or result from DNA replication errors (R). We studied the relationship between the number of …
or result from DNA replication errors (R). We studied the relationship between the number of …
[HTML][HTML] The molecular taxonomy of primary prostate cancer
There is substantial heterogeneity among primary prostate cancers, evident in the spectrum
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …
Tumor microenvironment targeted nanotherapeutics for cancer therapy and diagnosis: A review
S Thakkar, D Sharma, K Kalia, RK Tekade - Acta biomaterialia, 2020 - Elsevier
Recent findings suggest that the cellular and extracellular materials surrounding the
cancerous cells from an atypical tumor microenvironment (TM) play a pivotal role in the …
cancerous cells from an atypical tumor microenvironment (TM) play a pivotal role in the …
The cell cycle, cancer development and therapy
E Jamasbi, M Hamelian, MA Hossain… - Molecular biology reports, 2022 - Springer
The process of cell division plays a vital role in cancer progression. Cell proliferation and
error-free chromosomes segregation during mitosis are central events in life cycle. Mistakes …
error-free chromosomes segregation during mitosis are central events in life cycle. Mistakes …
Anticancer properties of essential oils and other natural products
Essential oils are secondary metabolites with a key‐role in plants protection, consisting
primarily of terpenes with a volatile nature and a diverse array of chemical structures …
primarily of terpenes with a volatile nature and a diverse array of chemical structures …
[HTML][HTML] Exploring the potent anticancer activity of essential oils and their bioactive compounds: Mechanisms and prospects for future cancer therapy
Cancer is one of the leading causes of death worldwide, affecting millions of people each
year. Fortunately, the last decades have been marked by considerable advances in the field …
year. Fortunately, the last decades have been marked by considerable advances in the field …
The ferric reducing/antioxidant power (FRAP) assay for non‐enzymatic antioxidant capacity: concepts, procedures, limitations and applications
IFF Benzie, M Devaki - … of antioxidant activity & capacity: Recent …, 2018 - Wiley Online Library
This chapter presents concepts, technical tips and calculations, along with some illustrative
examples of how the ferric reducing/antioxidant power (FRAP) assay has been applied in …
examples of how the ferric reducing/antioxidant power (FRAP) assay has been applied in …
Genetic etiology of oral cancer
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide. It accounts for 2.5% of all new cancer cases and 1.9% of all cancer deaths …
worldwide. It accounts for 2.5% of all new cancer cases and 1.9% of all cancer deaths …