Protein structure prediction is a way to bridge the sequence-structure gap, one of the main
challenges in computational biology and chemistry. Predicting any protein's accurate …

Oligomers which form during amyloid fibril assembly are considered to be key contributors
towards amyloid disease. However, understanding how such intermediates form, their …

CXCR1 is one of two high-affinity receptors for the CXC chemokine interleukin-8 (IL-8), a
major mediator of immune and inflammatory responses implicated in many disorders …

The 3D solution structure of the GCC‐box binding domain of a protein from Arabidopsis
thaliana in complex with its target DNA fragment has been determined by heteronuclear …

Revised Manuscript Received December 16, 1994® abstract: The amino acid sequence and
structure of a uterotonic polypeptide extracted from the African plant Oldenlandia affinis DC …

The field of drug discovery has witnessed infinite development over the last decade with the
demand for discovery of novel efficient lead compounds. Although the development of novel …

Since the 1980s, deep learning and biomedical data have been coevolving and feeding
each other. The breadth, complexity, and rapidly expanding size of biomedical data have …

We report the solution structure of BID, an intracellular cross-talk agent that can amplify
FAS/TNF apoptotic signal through the mitochondria death pathway after Caspase 8 …

Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney
Diseases, National Institutes of Health, Bethesda, Maryland 20892, Department of Molecular …

Surface proteins of Gram-positive bacteria play important roles during the pathogenesis of
human infections and require sortase for anchoring to the cell-wall envelope. Sortase …