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Lipid droplets in the nervous system
Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …
physiological state of cells. In addition to controlling cell metabolism, they play a protective …
Understanding axon guidance: are we nearly there yet?
During nervous system development, neurons extend axons to reach their targets and form
functional circuits. The faulty assembly or disintegration of such circuits results in disorders …
functional circuits. The faulty assembly or disintegration of such circuits results in disorders …
[HTML][HTML] Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity
Summary Cannabidiol (CBD), a non-euphoric component of cannabis, reduces seizures in
multiple forms of pediatric epilepsies, but the mechanism (s) of anti-seizure action remain …
multiple forms of pediatric epilepsies, but the mechanism (s) of anti-seizure action remain …
Lysophospholipid mediators in health and disease
Lysophospholipids, exemplified by lysophosphatidic acid (LPA) and sphingosine 1-
phosphate (S1P), are produced by the metabolism and perturbation of biological …
phosphate (S1P), are produced by the metabolism and perturbation of biological …
Endocannabinoids and related N-acylethanolamines: biological activities and metabolism
K Tsuboi, T Uyama, Y Okamoto, N Ueda - Inflammation and Regeneration, 2018 - Springer
The plant Cannabis sativa contains cannabinoids represented by Δ 9-tetrahydrocannabinol,
which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2 …
which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2 …
[HTML][HTML] Plasmalogens, platelet-activating factor and beyond–Ether lipids in signaling and neurodegeneration
Glycerol-based ether lipids including ether phospholipids form a specialized branch of lipids
that in mammals require peroxisomes for their biosynthesis. They are major components of …
that in mammals require peroxisomes for their biosynthesis. They are major components of …
Brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis
The development of Alzheimer's dementia (AD) accompanies both central and peripheral
metabolic disturbance, but the metabolic basis underlying AD and metabolic markers …
metabolic disturbance, but the metabolic basis underlying AD and metabolic markers …
Roles of axon guidance molecules in neuronal wiring in the develo** spinal cord
The spinal cord receives, relays and processes sensory information from the periphery and
integrates this information with descending inputs from supraspinal centres to elicit precise …
integrates this information with descending inputs from supraspinal centres to elicit precise …
Fingolimod: lessons learned and new opportunities for treating multiple sclerosis and other disorders
Fingolimod (FTY720, Gilenya) was the first US Food and Drug Administration–approved oral
therapy for relapsing forms of multiple sclerosis (MS). Research on modified fungal …
therapy for relapsing forms of multiple sclerosis (MS). Research on modified fungal …
Some prospective alternatives for treating pain: the endocannabinoid system and its putative receptors GPR18 and GPR55
Background: Marijuana extracts (cannabinoids) have been used for several millennia for
pain treatment. Regarding the site of action, cannabinoids are highly promiscuous …
pain treatment. Regarding the site of action, cannabinoids are highly promiscuous …