Radiogenomics: a key component of precision cancer medicine

Z Liu, T Duan, Y Zhang, S Weng, H Xu, Y Ren… - British Journal of …, 2023 - nature.com
Radiogenomics, focusing on the relationship between genomics and imaging phenotypes,
has been widely applied to address tumour heterogeneity and predict immune …

[HTML][HTML] Predicting gene mutation status via artificial intelligence technologies based on multimodal integration (MMI) to advance precision oncology

J Shao, J Ma, Q Zhang, W Li, C Wang - Seminars in cancer biology, 2023 - Elsevier
Personalized treatment strategies for cancer frequently rely on the detection of genetic
alterations which are determined by molecular biology assays. Historically, these processes …

Predicting EGFR mutation status in non–small cell lung cancer using artificial intelligence: a systematic review and meta-analysis

HS Nguyen, DKN Ho, NN Nguyen, HM Tran… - Academic …, 2024 - Elsevier
Rationale and Objectives Recent advancements in artificial intelligence (AI) render a
substantial promise for epidermal growth factor receptor (EGFR) mutation status prediction …

Feature selection methods and predictive models in CT lung cancer radiomics

G Ge, J Zhang - Journal of applied clinical medical physics, 2023 - Wiley Online Library
Radiomics is a technique that extracts quantitative features from medical images using data‐
characterization algorithms. Radiomic features can be used to identify tissue characteristics …

Towards machine learning-aided lung cancer clinical routines: Approaches and open challenges

F Silva, T Pereira, I Neves, J Morgado… - Journal of Personalized …, 2022 - mdpi.com
Advancements in the development of computer-aided decision (CAD) systems for clinical
routines provide unquestionable benefits in connecting human medical expertise with …

Radiomics under 2D regions, 3D regions, and peritumoral regions reveal tumor heterogeneity in non-small cell lung cancer: a multicenter study

X Zhang, G Zhang, X Qiu, J Yin, W Tan, X Yin… - La radiologia …, 2023 - Springer
Purpose Lung cancer has significant genetic and phenotypic heterogeneity, leading to poor
prognosis. Radiomic features have emerged as promising predictors of the tumor …

Radiogenomic system for non-invasive identification of multiple actionable mutations and PD-L1 expression in non-small cell lung cancer based on CT images

J Shao, J Ma, S Zhang, J Li, H Dai, S Liang, Y Yu, W Li… - Cancers, 2022 - mdpi.com
Simple Summary Actional mutations and PD-L1 expression are of paramount importance for
the precision treatment of lung cancer. Radiogenomics is a promising field that integrated …

Deep radiotranscriptomics of non-small cell lung carcinoma for assessing molecular and histology subtypes with a data-driven analysis

E Trivizakis, J Souglakos, A Karantanas, K Marias - Diagnostics, 2021 - mdpi.com
Radiogenomic and radiotranscriptomic studies have the potential to pave the way for a
holistic decision support system built on genomics, transcriptomics, radiomics, deep features …

Novel tools for early diagnosis and precision treatment based on artificial intelligence

J Shao, J Feng, J Li, S Liang, W Li… - Chinese Medical Journal …, 2023 - mednexus.org
Lung cancer has the highest mortality rate among all cancers in the world. Hence, early
diagnosis and personalized treatment plans are crucial to improving its 5-year survival rate …

p53 genetics and biology in lung carcinomas: insights, implications and clinical applications

DA Benitez, G Cumplido-Laso, M Olivera-Gómez… - Biomedicines, 2024 - mdpi.com
The TP53 gene is renowned as a tumor suppressor, playing a pivotal role in overseeing the
cell cycle, apoptosis, and maintaining genomic stability. Dysregulation of p53 often …