Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …

Nanomaterials (NMs) are widely used in commercial and medical products, such as
cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal …

While oral desensitization is capable of alleviating peanut allergen anaphylaxis, long-term
immune tolerance is the sought-after goal. We developed a liver-targeting lipid nanoparticle …

Easy recurrence and strong treatment side effects significantly limit the clinical treatment of
allergic dermatitis. The human trace element selenium (Se) plays essential roles in redox …

Extravasation is the first step for nanomedicines in circulation to reach targeted solid tumors.
Traditional nanomedicines have been designed to extravasate into tumor interstitium …

In addition to the contribution of cancer cells, the solid tumor microenvironment (TME) has a
critical role in determining tumor expansion, antitumor immunity, and the response to …

Nucleic acid vaccines, especially messenger RNA (mRNA) vaccines, display unique
benefits in the current COVID-19 pandemic. The application of polymeric materials as …

Nanotechnology has emerged as a transformative pathway in vaccine research and
delivery. Nanovaccines, encompassing lipid and nonlipid formulations, exhibit considerable …

Recent advancements in RNA therapeutics highlight the critical need for precision gene
delivery systems that target specific organs and cells. Lipid nanoparticles (LNPs) have …

Liver fibrosis is a reversible disease course caused by various liver injury etiologies, and it
can lead to severe complications, such as liver cirrhosis, liver failure, and even liver cancer …