[HTML][HTML] The pathophysiology of long COVID throughout the renin-angiotensin system

S Khazaal, J Harb, M Rima, C Annweiler, Y Wu, Z Cao… - Molecules, 2022 - mdpi.com
COVID-19 has expanded across the world since its discovery in Wuhan (China) and has
had a significant impact on people's lives and health. Long COVID is a term coined by the …

[HTML][HTML] mRNA: vaccine or gene therapy? The safety regulatory issues

H Banoun - International Journal of Molecular Sciences, 2023 - mdpi.com
COVID-19 vaccines were developed and approved rapidly in response to the urgency
created by the pandemic. No specific regulations existed at the time they were marketed …

[HTML][HTML] Role of SARS-COV-2 and ACE2 in the pathophysiology of peripheral vascular diseases

H Tanzadehpanah, E Lotfian, A Avan, S Saki… - Biomedicine & …, 2023 - Elsevier
The occurrence of a novel coronavirus known as severe acute respiratory syndrome-
coronavirus-2 (SARS-CoV-2), created a serious challenge worldwide. SARS-CoV-2 has …

COVID-19 and atrial fibrillation: Intercepting lines

M Donniacuo, A De Angelis, C Rafaniello… - Frontiers in …, 2023 - frontiersin.org
Almost 20% of COVID-19 patients have a history of atrial fibrillation (AF), but also a new-
onset AF represents a frequent complication in COVID-19. Clinical evidence demonstrates …

COVID-19 induced liver injury from a new perspective: mitochondria

H Akbari, F Taghizadeh-Hesary - Mitochondrion, 2023 - Elsevier
Liver damage is a common sequela of COVID-19 (coronavirus disease 2019), worsening
the clinical outcomes. However, the underlying mechanism of COVID-induced liver injury …

[HTML][HTML] Treating COVID-19 with medicinal plants: is it even conceivable? A comprehensive review

H Al-Jamal, S Idriss, R Roufayel, Z Abi Khattar… - Viruses, 2024 - mdpi.com
In 2020, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) challenged the
world with a global outbreak that led to millions of deaths worldwide. Coronavirus disease …

[HTML][HTML] Vascular implications of COVID-19: role of radiological imaging, artificial intelligence, and tissue characterization: a special report

NN Khanna, M Maindarkar, A Puvvula, S Paul… - Journal of …, 2022 - mdpi.com
The SARS-CoV-2 virus has caused a pandemic, infecting nearly 80 million people
worldwide, with mortality exceeding six million. The average survival span is just 14 days …

Quercetin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and activation of JAK2/STAT3 pathway: a target based networking pharmacology …

D Wang, F Ali, H Liu, Y Cheng, M Wu… - Frontiers in …, 2022 - frontiersin.org
The rapid growth of vascular smooth muscle cells (VSMCs) represents crucial pathological
changes during the development of hypertensive vascular remodeling. Although quercetin …

Aprotinin (II): Inhalational Administration for the Treatment of COVID-19 and Other Viral Conditions

JF Padín, JM Pérez-Ortiz… - International Journal of …, 2024 - mdpi.com
Aprotinin is a broad-spectrum inhibitor of human proteases that has been approved for the
treatment of bleeding in single coronary artery bypass surgery because of its potent …

Unraveling the underlying molecular mechanism of 'Silent Hypoxia'in COVID-19 patients suggests a central role for angiotensin II modulation of the AT1R-hypoxia …

CA Devaux, JC Lagier - Journal of Clinical Medicine, 2023 - mdpi.com
A few days after being infected with SARS-CoV-2, a fraction of people remain asymptomatic
but suffer from a decrease in arterial oxygen saturation in the absence of apparent dyspnea …