[HTML][HTML] Chemical constituents of Panax ginseng and Panax notoginseng explain why they differ in therapeutic efficacy

H Liu, X Lu, Y Hu, X Fan - Pharmacological research, 2020 - Elsevier
Abstract Panax ginseng (Meyer) and Panax notoginseng (Burkill), belonging to the family
Araliaceae, are used worldwide as medicinal and functional herbs. Numerous publications …

Antidepressant active ingredients from herbs and nutraceuticals used in TCM: pharmacological mechanisms and prospects for drug discovery

YS Wang, CY Shen, JG Jiang - Pharmacological research, 2019 - Elsevier
Depression is a widespread psychological disorder that affects up to 20% of the world's
population. Traditional Chinese medicine (TCM), with its unique curative effect in depression …

Linking what we eat to our mood: a review of diet, dietary antioxidants, and depression

Q Huang, H Liu, K Suzuki, S Ma, C Liu - Antioxidants, 2019 - mdpi.com
Studies have shown that diet and nutrition play significant roles in the prevention of
depression and its clinical treatment. The present review aims to provide a clear …

[HTML][HTML] Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating …

B Ren, J Feng, N Yang, Y Guo, C Chen… - International …, 2021 - Elsevier
Abstract Background Ginsenoside Rg3 (Rg3), one of the most potent components extracted
from the roots of the traditional Chinese herb Panax ginseng, has prominent roles in anti …

Connection between systemic inflammation and neuroinflammation underlies neuroprotective mechanism of several phytochemicals in neurodegenerative diseases

J Wang, Y Song, Z Chen… - Oxidative medicine and …, 2018 - Wiley Online Library
Oxidative damage, mitochondrial dysfunction, and neuroinflammation are strongly
implicated in the pathogenesis of neurodegenerative diseases including Alzheimer's …

[HTML][HTML] Emerging targetome and signalome landscape of gut microbial metabolites

X Zheng, X Cai, H Hao - Cell metabolism, 2022 - cell.com
The gut microbiome produces chemically diverse small molecules to interact with the host,
conveying signals from the gut to the whole system. The microbial metabolites feature …

Panax notoginseng saponins: a review of its mechanisms of antidepressant or anxiolytic effects and network analysis on phytochemistry and pharmacology

W **e, X Meng, Y Zhai, P Zhou, T Ye, Z Wang, G Sun… - Molecules, 2018 - mdpi.com
Panax notoginseng (Burk) FH Chen, as traditional Chinese medicine, has a long history of
high clinical value, such as anti-inflammatory, anti-oxidation, inhibition of platelet …

Mechanisms of Panax ginseng action as an antidepressant

Y **, R Cui, L Zhao, J Fan, B Li - Cell proliferation, 2019 - Wiley Online Library
Objectives Panax ginseng, a well‐known traditional Chinese medicine with multiple
pharmacological activities, plays a crucial role in modulating mood disorders. Several recent …

[HTML][HTML] Traditional uses, chemical diversity and biological activities of Panax L.(Araliaceae): A review

L Liu, FR Xu, YZ Wang - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Panax L.(Araliaceae) is globally-recognized plant
resource suitable for the globalization of traditional Chinese medicines. It has traditionally …

Traditional Chinese medicine in depression treatment: from molecules to systems

C Li, J Huang, YC Cheng, YW Zhang - Frontiers in Pharmacology, 2020 - frontiersin.org
Depression is a multigenetic or multifactorial syndrome. The central neuron system (CNS)-
orientated, single target, and conventional antidepressants are insufficient and far from …