Strain and elasticity imaging in compression optical coherence elastography: the two‐decade perspective and recent advances

VY Zaitsev, AL Matveyev, LA Matveev… - Journal of …, 2021 - Wiley Online Library
Quantitative map** of deformation and elasticity in optical coherence tomography has
attracted much attention of researchers during the last two decades. However, despite …

Stem cell mechanobiology and the role of biomaterials in governing mechanotransduction and matrix production for tissue regeneration

SM Naqvi, LM McNamara - Frontiers in bioengineering and …, 2020 - frontiersin.org
Mechanobiology has underpinned many scientific advances in understanding how
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …

Histological validation of in vivo assessment of cancer tissue inhomogeneity and automated morphological segmentation enabled by Optical Coherence Elastography

AA Plekhanov, MA Sirotkina, AA Sovetsky… - Scientific reports, 2020 - nature.com
We present a non-invasive (albeit contact) method based on Optical Coherence
Elastography (OCE) enabling the in vivo segmentation of morphological tissue constituents …

Mechanical properties of cell sheets and spheroids: the link between single cells and complex tissues

YM Efremov, IM Zurina, VS Presniakova… - Biophysical …, 2021 - Springer
Cell aggregates, including sheets and spheroids, represent a simple yet powerful model
system to study both biochemical and biophysical intercellular interactions. However, it is …

3D volumetric mechanosensation of MCF7 breast cancer spheroids in a linear stiffness gradient GelAGE

D Vahala, SE Amos, M Sacchi… - Advanced …, 2023 - Wiley Online Library
The tumor microenvironment presents spatiotemporal shifts in biomechanical properties with
cancer progression. Hydrogel biomaterials like GelAGE offer the stiffness tuneability to …

Modeling the extracellular matrix in cell migration and morphogenesis: a guide for the curious biologist

RM Crossley, S Johnson, E Tsingos, Z Bell… - Frontiers in cell and …, 2024 - frontiersin.org
The extracellular matrix (ECM) is a highly complex structure through which biochemical and
mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a …

[HTML][HTML] Tumor spheroid elasticity estimation using mechano-microscopy combined with a conditional generative adversarial network

KY Foo, B Shaddy, J Murgoitio-Esandi… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objectives Techniques for imaging the mechanical properties of
cells are needed to study how cell mechanics influence cell function and disease …

Real-time strain and elasticity imaging in phase-sensitive optical coherence elastography using a computationally efficient realization of the vector method

VY Zaitsev, SY Ksenofontov, AA Sovetsky… - Photonics, 2021 - mdpi.com
We present a real-time realization of OCT-based elastographic map** local strains and
distribution of the Young's modulus in biological tissues, which is in high demand for …

Analysis of friction in quantitative micro-elastography

KL Metzner, Q Fang, RW Sanderson… - Biomedical Optics …, 2023 - opg.optica.org
Quantitative micro-elastography (QME) is a compression-based optical coherence
elastography technique capable of measuring the mechanical properties of tissue on the …

Analysis of strain estimation methods in phase-sensitive compression optical coherence elastography

J Li, E Pijewska, Q Fang, M Szkulmowski… - Biomedical Optics …, 2022 - opg.optica.org
In compression optical coherence elastography (OCE), deformation is quantified as the local
strain at each pixel in the OCT field-of-view. A range of strain estimation methods have been …