Superoxide dismutases and superoxide reductases

Y Sheng, IA Abreu, DE Cabelli, MJ Maroney… - Chemical …, 2014 - ACS Publications
Superoxide, O2•−, is formed in all living organisms that come in contact with air, and,
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …

Tetraspanins: structure, dynamics, and principles of partner-protein recognition

KJ Susa, AC Kruse, SC Blacklow - Trends in cell biology, 2024 - cell.com
Tetraspanins are a large, highly conserved family of four-pass transmembrane (TM) proteins
that play critical roles in a variety of essential cellular functions, including cell migration …

Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost

F Muecksch, Z Wang, A Cho, C Gaebler, T Ben Tanfous… - Nature, 2022 - nature.com
The Omicron variant of SARS-CoV-2 infected many vaccinated and convalescent
individuals,–. Despite the reduced protection from infection, individuals who received three …

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

H Ashkenazy, S Abadi, E Martz, O Chay… - Nucleic acids …, 2016 - academic.oup.com
The degree of evolutionary conservation of an amino acid in a protein or a nucleic acid in
DNA/RNA reflects a balance between its natural tendency to mutate and the overall need to …

[HTML][HTML] Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies

CO Barnes, AP West, KE Huey-Tubman… - Cell, 2020 - cell.com
Neutralizing antibody responses to coronaviruses mainly target the receptor-binding domain
(RBD) of the trimeric spike. Here, we characterized polyclonal immunoglobulin Gs (IgGs) …

Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice

AA Cohen, PNP Gnanapragasam, YE Lee, PR Hoffman… - Science, 2021 - science.org
Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and
SARS-related emergent zoonotic coronaviruses is urgently needed. We made homotypic …

Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models

AA Cohen, N van Doremalen, AJ Greaney, H Andersen… - Science, 2022 - science.org
To combat future severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health …

Dali server: conservation map** in 3D

L Holm, P Rosenstrï¿ ½m - Nucleic acids research, 2010 - academic.oup.com
Abstract Our web site (http://ekhidna. biocenter. helsinki. fi/dali_server) runs the Dali
program for protein structure comparison. The web site consists of three parts:(i) the Dali …

EAACI molecular allergology user's guide

PM Matricardi, J Kleine‐Tebbe… - Pediatric Allergy and …, 2016 - Wiley Online Library
The availability of allergen molecules ('components') from several protein families has
advanced our understanding of immunoglobulin E (IgE)‐mediated responses and enabled …

NAD+ cleavage activity by animal and plant TIR domains in cell death pathways

S Horsefield, H Burdett, X Zhang, MK Manik, Y Shi… - Science, 2019 - science.org
SARM1 (sterile alpha and TIR motif containing 1) is responsible for depletion of
nicotinamide adenine dinucleotide in its oxidized form (NAD+) during Wallerian …