The complexation of biogenic molecules with metals is the widespread strategy in screening
for new pharmaceuticals with improved therapeutic and physicochemical properties. This …

In order to explore the relationship between the antioxidant activity and structure of fifteen
benzofuran derivatives, we carried out a QSAR study using multiple linear regression (MLR) …

Background: Alterations in GABAnergic system are implicated in the pathophysiology of
schizophrenia. Available antipsychotics that target GABA receptor form a desirable …

Electronic structures, the effect of the substitution, structure physicochemical property/activity
relationships and drug-likeness applied in pyrazine derivatives, have been studied at ab …

Context: In the last decade, resistance to epidermal growth factor receptor-tyrosine kinase
inhibitors (EGFR-TKIs) in lung cancer cases has been widespread. The discovery and …

Context: In the last decade, antimicrobial resistance cases have been widespread. The
discovery and development of new drugs need to be done to overcome the case. Some …

Flavones are secondary metabolite products in plants and have broad-spectrum effects in
both microorganisms and animals with varied structures and functions. The description of …

Background: 6-Fluoro-3-(4H-1, 2, 4-triazol-3-yl) quinolin-4 (1H)-ones are promising
antitumor agents with enormous data on their profound cytotoxic effects on the human …

Context A large number of heterocyclic compounds are used as drugs, mainly due to the
duality of lipophilicity playing in hydrophobic interactions and solubility with at least one …

QSAR, Quantitative structure-activity relationship has paved a way for itself into the practice
of agrochemistry, pharmaceutical chemistry, toxicology and eventually most faces of …