Facts and hopes in immunotherapy of endometrial cancer
JA Marín-Jiménez, S García-Mulero, X Matías-Guiu… - Clinical Cancer …, 2022 - AACR
Immunotherapy with checkpoint inhibitors has changed the paradigm of treatment for many
tumors, and endometrial carcinoma is not an exception. Approved treatment options are …
tumors, and endometrial carcinoma is not an exception. Approved treatment options are …
Molecular subtypes of endometrial cancer: Implications for adjuvant treatment strategies
Y Yang, SF Wu, W Bao - International Journal of Gynecology & …, 2024 - Wiley Online Library
Background When determining adjuvant treatment for endometrial cancer, the decision
typically relies on factors such as cancer stage, histologic grade, subtype, and a few …
typically relies on factors such as cancer stage, histologic grade, subtype, and a few …
IgA-dominated humoral immune responses govern patients' outcome in endometrial cancer
Recent studies suggest that B cells could play an important role in the tumor
microenvironment. However, the role of humoral responses in endometrial cancer remains …
microenvironment. However, the role of humoral responses in endometrial cancer remains …
Endometrial carcinoma: immune microenvironment and emerging treatments in immuno-oncology
S Rousset-Rouviere, P Rochigneux, AS Chretien… - Biomedicines, 2021 - mdpi.com
Endometrial cancer (EC) can easily be cured when diagnosed at an early stage. However,
advanced and metastatic EC is a common disease, affecting more than 15,000 patients per …
advanced and metastatic EC is a common disease, affecting more than 15,000 patients per …
Immune checkpoint inhibitors and mismatch repair status in advanced endometrial cancer: elective affinities
A Rizzo - Journal of clinical medicine, 2022 - mdpi.com
Since endometrial cancers (ECs) are frequently TMB-H and MSI-H/dMMR tumors, this
element has provided the rationale for testing immune checkpoint inhibitors (ICIs), which …
element has provided the rationale for testing immune checkpoint inhibitors (ICIs), which …
CDK4/6 blockade provides an alternative approach for treatment of mismatch-repair deficient tumors
I Salewski, J Henne, L Engster, P Krone… - …, 2022 - Taylor & Francis
Mismatch repair-deficient (dMMR) tumors show a good response toward immune checkpoint
inhibitors (ICI), but develo** resistance impairs patients' outcomes. Here, we compared …
inhibitors (ICI), but develo** resistance impairs patients' outcomes. Here, we compared …
Inflammation-related LncRNAs signature for prognosis and immune response evaluation in uterine corpus endometrial carcinoma
H Gu, J Song, Y Chen, Y Wang, X Tan, H Zhao - Frontiers in oncology, 2022 - frontiersin.org
Backgrounds Uterine corpus endometrial carcinoma (UCEC) is one of the greatest threats
on the female reproductive system. The aim of this study is to explore the inflammation …
on the female reproductive system. The aim of this study is to explore the inflammation …
Importance of the endometrial immune environment in endometrial cancer and associated therapies
Endometrial cancer is rising in prevalence. The standard treatment modality of hysterectomy
is becoming increasingly inadequate due primarily to the direct link between endometrial …
is becoming increasingly inadequate due primarily to the direct link between endometrial …
The potential role of methyltransferase-like 5 in deficient mismatch repair of uterine corpus endometrial carcinoma
X Liu, H Ma, L Ma, K Li, Y Kang - Bioengineered, 2022 - Taylor & Francis
To explore the potential function of methyltransferase-like 5 (METTL5) in uterine corpus
endometrial carcinoma (UCEC) and verify the relationship between deficient DNA mismatch …
endometrial carcinoma (UCEC) and verify the relationship between deficient DNA mismatch …
ImmuneScore of eight-gene signature predicts prognosis and survival in patients with endometrial cancer
J Gu, Z Wang, BO Wang, X Ma - Frontiers in Oncology, 2023 - frontiersin.org
Background Endometrial cancer (EC) is a common gynecological cancer worldwide and the
sixth most common female malignant tumor. A large number of studies conducted through …
sixth most common female malignant tumor. A large number of studies conducted through …