Measuring disease severity in inflammatory bowel disease–Beyond treat to target
A Swaminathan, AS Day, MP Sparrow… - Alimentary …, 2024 - Wiley Online Library
Background Inflammatory bowel disease (IBD) follows a heterogenous disease course and
predicting a patient's prognosis is challenging. There is a wide burden of illness in IBD and …
predicting a patient's prognosis is challenging. There is a wide burden of illness in IBD and …
The future of precision medicine to predict outcomes and control tissue remodeling in inflammatory bowel disease
CA Lamb, A Saifuddin, N Powell, F Rieder - Gastroenterology, 2022 - Elsevier
Inflammatory bowel disease is characterized by significant interindividual heterogeneity.
With a wider selection of pharmacologic and nonpharmacologic interventions available and …
With a wider selection of pharmacologic and nonpharmacologic interventions available and …
Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis
Z Wei, S Hang, DK Wiredu Ocansey, Z Zhang… - Journal of …, 2023 - Springer
Background Ferroptosis, a unique form of non-apoptotic cell death, is dependent on iron and
lipoperoxidation, and has been shown to be associated with the pathogenesis of …
lipoperoxidation, and has been shown to be associated with the pathogenesis of …
Digital health technologies for remote monitoring and management of inflammatory bowel disease: a systematic review
NH Nguyen, I Martinez, A Atreja… - Official journal of the …, 2022 - journals.lww.com
METHODS: Through a systematic review of multiple databases through August 31, 2020, we
identified randomized controlled trials in patients with IBD comparing digital health …
identified randomized controlled trials in patients with IBD comparing digital health …
Artificial intelligence in inflammatory bowel disease endoscopy: implications for clinical trials
Artificial intelligence shows promise for clinical research in inflammatory bowel disease
endoscopy. Accurate assessment of endoscopic activity is important in clinical practice and …
endoscopy. Accurate assessment of endoscopic activity is important in clinical practice and …
[HTML][HTML] Integrating evidence to guide use of biologics and small molecules for inflammatory bowel diseases
Advances in science have led to the development of multiple biologics and small molecules
for the treatment of inflammatory bowel diseases (IBDs). This growth in advanced medical …
for the treatment of inflammatory bowel diseases (IBDs). This growth in advanced medical …
Interpreting modern randomized controlled trials of medical therapy in inflammatory bowel disease
Abstract Treatment options for the medical management of inflammatory bowel disease
(IBD) have expanded substantially over the past decade. Multiple classes of advanced …
(IBD) have expanded substantially over the past decade. Multiple classes of advanced …
Personalized (N-of-1) clinical trials for inflammatory bowel disease: opportunities and challenges
Abstract Background and Aims Heterogeneity of treatment effects in inflammatory bowel
disease means that many individuals or patient subgroups depart from the average for …
disease means that many individuals or patient subgroups depart from the average for …
Artificial intelligence and endo-histo-omics: new dimensions of precision endoscopy and histology in inflammatory bowel disease
M Iacucci, G Santacroce, I Zammarchi… - The Lancet …, 2024 - thelancet.com
Integrating artificial intelligence into inflammatory bowel disease (IBD) has the potential to
revolutionise clinical practice and research. Artificial intelligence harnesses advanced …
revolutionise clinical practice and research. Artificial intelligence harnesses advanced …
Screening failure in a large clinical trial centre for inflammatory bowel diseases: rates, causes, and outcomes
A Outtier, L Gijbels, M Noman… - Inflammatory Bowel …, 2023 - academic.oup.com
Background Patients with inflammatory bowel diseases (IBD) sometimes require
investigational medicinal therapy in a clinical trial. Before enrollment, patients must meet …
investigational medicinal therapy in a clinical trial. Before enrollment, patients must meet …