In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

Intermediate species in the assembly of amyloid filaments are believed to play a central role
in neurodegenerative diseases and may constitute important targets for therapeutic …

The function of bio-macromolecules is determined by both their 3D structure and
conformational dynamics. These molecules are inherently flexible systems displaying a …

NMR spectroscopy is an indispensably powerful technique for the analysis of biomolecules
under ambient conditions, both for structural-and functional studies. However, in practice the …

Sixteen ovarian tumor (OTU) family deubiquitinases (DUBs) exist in humans, and most
members regulate cell-signaling cascades. Several OTU DUBs were reported to be ubiquitin …

Many viruses are known to form cellular compartments, also called viral factories.
Paramyxoviruses, including measles virus, colocalize their proteomic and genomic material …

The aggregation of the microtubule-associated tau protein and formation of" neurofibrillary
tangles" is one of the hallmarks of Alzheimer disease. The mechanisms underlying the …

Chemical shifts contain important site-specific information on the structure and dynamics of
proteins. Deviations from statistical average values, known as random coil chemical shifts …

FtsA is an early component of the Z‐ring, the structure that divides most bacteria, formed by
tubulin‐like FtsZ. FtsA belongs to the actin family of proteins, showing an unusual …

The early phases of clathrin mediated endocytosis are organized through a highly complex
interaction network mediated by clathrin associated sorting proteins (CLASPs) that comprise …